Platelet Chemiluminescence during Physical Exercise of Various Intensity


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Generation of ROS (including free radicals) in rat platelets during physical exercises of different intensities was evaluated by the chemiluminescent method. The acute or chronic submaximal exercises increased the platelet chemiluminescence by 2.5-3.0 times. In the control, platelet activation with physiological aggregant ADP enhanced their chemiluminescence by 7.5 times. Addition of ADP to platelets isolated from animals subjected to exercise of any intensity increased chemiluminescence by 4-5 times. In a trained organism, functional reserve of the platelets is preserved during long-term physical exercise of any intensity, but is exhausted after acute physical exercise. Thus, intensive physical exercises enhanced the hemostatic potential of the blood, which is associated with the risk of thrombohemorrhagic complications, especially in acute or submaximal long-term exercises.

作者简介

V. Sergienko

Federal Scientific Clinical Center of Physico-Chemical Medicine

Email: ermen33@mail.ru
俄罗斯联邦, Moscow

S. Kantyukov

South-Ural State Medical University

Email: ermen33@mail.ru
俄罗斯联邦, Moscow

E. Ermolaeva

South-Ural State Medical University

编辑信件的主要联系方式.
Email: ermen33@mail.ru
俄罗斯联邦, Moscow

S. Sashenkov

South-Ural State Medical University

Email: ermen33@mail.ru
俄罗斯联邦, Moscow

E. Surina-Marysheva

South-Ural State University

Email: ermen33@mail.ru
俄罗斯联邦, Chelyabinsk

I. Medvedeva

Tyumen State Medical University

Email: ermen33@mail.ru
俄罗斯联邦, Tyumen

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