Involvement of dihydropyridine-sensitive calcium channels in high asynchrony of transmitter release in neuromuscular synapses of newborn rats


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Abstract

Experiments on neuromuscular synapses of rats at different stages of ontogenesis have been performed. It has been found that one of the reasons of higher asynchrony of the release of single quanta of acetylcholine in the synapses of newborn animals is the activity of the presynaptic dihydropyridine-sensitive calcium channels of the L-type.

About the authors

V. F. Khuzakhmetova

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: ellyab@mail.ru
Russian Federation, Kazan, Tatarstan; Kazan, Tatarstan

L. F. Nurullin

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: ellyab@mail.ru
Russian Federation, Kazan, Tatarstan; Kazan, Tatarstan

E. A. Bukharaeva

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Author for correspondence.
Email: ellyab@mail.ru
Russian Federation, Kazan, Tatarstan; Kazan, Tatarstan

E. E. Nikolsky

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University; Kazan State Medical University

Email: ellyab@mail.ru
Russian Federation, Kazan, Tatarstan; Kazan, Tatarstan; Kazan, Tatarstan

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