Chronic cold stress modulates the function of peritoneal macrophages in vivo
- Authors: Gein S.V.1,2, Sharav’eva I.L.1
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Affiliations:
- Institute of Ecology and Genetics of Microorganisms, Ural Branch
- Perm National Research State University
- Issue: Vol 474, No 1 (2017)
- Pages: 129-131
- Section: Cell Biology
- URL: https://journal-vniispk.ru/0012-4966/article/view/154086
- DOI: https://doi.org/10.1134/S0012496617030127
- ID: 154086
Cite item
Abstract
On day 7 of chronic cold stress, concentration of corticosterone in plasma was established to increase, zymosan-induced production of reactive oxygen species was activated, and IL-10 synthesis by macrophages was enhanced regardless of the opiate receptor blockade. Increase in the concentration of corticosterone was independent of the blockade of opioid receptors, whereas the zymosan-induced increase in the production of oxygen radicals and activation of the spontaneous production of IL-10 was blocked in mice by naloxone. Chronic cold stress had no effect on the production of IL-1β and TNF-α.
About the authors
S. V. Gein
Institute of Ecology and Genetics of Microorganisms, Ural Branch; Perm National Research State University
Author for correspondence.
Email: gein@iegm.ru
Russian Federation, Perm, 614081; Perm, 614990
I. L. Sharav’eva
Institute of Ecology and Genetics of Microorganisms, Ural Branch
Email: gein@iegm.ru
Russian Federation, Perm, 614081
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