Deuterium Oxide Enhances  Escherichia coli  SOS Response Induced by Genotoxicants

S. K. Abilev; S. V. Smirnova; E. V. Igonina; V. N. Parmon; N. K. Yankovsky

doi:10.1134/S0012496618030031

Deuterium Oxide Enhances Escherichia coli SOS Response Induced by Genotoxicants

Authors: Abilev S.K.¹^,2, Smirnova S.V.¹, Igonina E.V.¹, Parmon V.N.³, Yankovsky N.K.¹^,2
Affiliations:
1. Vavilov Institute of General Genetics
2. Faculty of Biology
3. Boreskov Institute of Catalysis, Siberian Branch
Issue: Vol 480, No 1 (2018)
Pages: 85-89
Section: General Biology
URL: https://journal-vniispk.ru/0012-4966/article/view/154270
DOI: https://doi.org/10.1134/S0012496618030031
ID: 154270

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Abstract

It has been demonstrated that deuterium oxide enhances the SOS response of Escherichia coli cells induced by chemical genotoxicants and mutagens. This demonstrates that the heavy nonradioactive hydrogen isotope deuterium can be considered to be a comutagen.