Email this article Evaluation of Individual Risk Factors of Alcohol Preference in Rats
- Authors: Egorov A.Y.1,2,3, Demianko I.V.4, Filatova E.V.1
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Affiliations:
- Sechenov Institute of Evolutionary Physiology and Biochemistry
- St. Petersburg State University
- Ministry of Health of the Russian Federation
- Herzen Russian State Pedagogical University
- Issue: Vol 481, No 1 (2018)
- Pages: 128-131
- Section: Physiology
- URL: https://journal-vniispk.ru/0012-4966/article/view/154316
- DOI: https://doi.org/10.1134/S0012496618040063
- ID: 154316
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Abstract
We evaluated individual risk factors of the development of alcohol preference in a model of voluntary alcohol consumption. Drinking behavior was estimated in the two-bottle test, and other behavioral features were studied in the open field test, test for social interaction, and marble burying test. The low adaptive capacity of an animal, which was manifested in a shorter time spent in the center of the open field, and low consumption of ethanol when the animal first tasted it were the leading factors of the subsequent preference of alcohol under the conditions of free choice.
About the authors
A. Yu. Egorov
Sechenov Institute of Evolutionary Physiology and Biochemistry; St. Petersburg State University; Ministry of Health of the Russian Federation
Author for correspondence.
Email: draegorov@mail.ru
Russian Federation, St. Petersburg, 194223; St. Petersburg, 199034; St. Petersburg
I. V. Demianko
Herzen Russian State Pedagogical University
Email: draegorov@mail.ru
Russian Federation, St. Petersburg, 191186
E. V. Filatova
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: draegorov@mail.ru
Russian Federation, St. Petersburg, 194223
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