Sucrose-enriched diet during maturation increases ethanol preference in rats


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Abstract

In the present study we used a diet enriched with 10% sucrose, which was consumed by adolescent animals of the experimental group for one month. We found that consumption of sweet food during sexual maturation affected alcohol preference, anxiety, and locomotor and exploratory activity in the adult rats. Our data show that easily available tasty food during adolescence probably impairs the reward system and serves as a trigger of future alcohol preference.

About the authors

M. V. Dorofeikova

Sechenov Institute of Evolutionary Physiology and Biochemistry

Author for correspondence.
Email: mvdorofeykova@mail.ru
Russian Federation, St. Petersburg

A. Yu. Egorov

Sechenov Institute of Evolutionary Physiology and Biochemistry; St. Petersburg State University; Mechnikov Northwestern State Medical University

Email: mvdorofeykova@mail.ru
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg

E. V. Filatova

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: mvdorofeykova@mail.ru
Russian Federation, St. Petersburg

A. A. Orlov

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: mvdorofeykova@mail.ru
Russian Federation, St. Petersburg

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