Cytokine pattern of the breast tumor supernatant
- 作者: Autenshlyus A.I.1,2, Kunts T.A.1, Karpukhina K.V.2, Mikhaylova E.S.1,2, Varaksin N.A.3, Marinkin I.O.1, Lyakhovich V.V.2
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隶属关系:
- Novosibirsk State Medical University
- Research Institute of Molecular Biology and Biophysics
- ZAO Vector Best
- 期: 卷 470, 编号 1 (2016)
- 页面: 247-248
- 栏目: Cell Biology
- URL: https://journal-vniispk.ru/0012-4966/article/view/153873
- DOI: https://doi.org/10.1134/S0012496616050057
- ID: 153873
如何引用文章
详细
Cytokine production was evaluated in supernatants of cultured tumor cells that were obtained by biopsy of the breast invasive ductal carcinoma (IDC) and breast fibroadenoma (FA) and grown in vitro. In the IDC supernatants, the concentrations of pro-inflammatory (pro-oncogenic) cytokines IL-17, IL-18, and IFNγ and of IL-1 receptor antagonist were significantly higher than in the FA cell supernatants. The concentrations of anti-inflammatory cytokine IL-10 and MCP-1 protein in supernatants of IDC cells were significantly lower than those determined in FA supernatants.
作者简介
A. Autenshlyus
Novosibirsk State Medical University; Research Institute of Molecular Biology and Biophysics
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
T. Kunts
Novosibirsk State Medical University
编辑信件的主要联系方式.
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk
K. Karpukhina
Research Institute of Molecular Biology and Biophysics
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk
E. Mikhaylova
Novosibirsk State Medical University; Research Institute of Molecular Biology and Biophysics
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
N. Varaksin
ZAO Vector Best
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk
I. Marinkin
Novosibirsk State Medical University
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk
V. Lyakhovich
Research Institute of Molecular Biology and Biophysics
Email: lpciip@211.ru
俄罗斯联邦, Novosibirsk
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