Free-radical chain oxidation of 1,4-dioxane inhibited by 2-thio-6-aminouracil

Abstract

The effect of 2-thio-6-aminouracil on the oxygen uptake kinetics has been studied in 1,4-dioxane free-radical chain oxidation as a model system. The presence of a thiocarbonyl group in the 2-position of the uracil ring makes 6-aminouracil highly reactive towards 1,4-dioxane peroxy radicals. The rate constant of the 1,4-dioxane peroxy radical interaction with 2-thio-6-aminouracil has been measured to be k₇ = (3.0 ± 0.5) × 10⁵ L mol^–1 s^–1 (333 K). The stoichiometric inhibition factor f = 1.1 ± 0.1 has been determined.