Felty syndrome as an orphan disease in the practice of a nurse
- Authors: Skvortsov V.V.1, Rodionova I.V.1, Chudasov M.A.1
-
Affiliations:
- FSBEI НЕ VolgSMU МОН Russia
- Issue: Vol 26, No 8 (2024)
- Pages: 30-32
- Section: Profession: theory and practice
- URL: https://journal-vniispk.ru/0025-8342/article/view/275704
- DOI: https://doi.org/10.29296/25879979-2024-08-05
- ID: 275704
Cite item
Abstract
Felty syndrome is a rare nosology. Being a complication of seropositive rheumatoid arthritis, Felty syndrome develops only in 1% of patients suffering from this disease for 10 years. SF occurs most often in women aged 40–50 years. SF significantly weakens the immune system and reduces the quality of human life. On average, the life expectancy of patients with Felty syndrome is more than 10 years. But in the case of an aggressive course, a fatal outcome is possible. To date, the diagnostic criteria are the presence of antinuclear antibodies (especially antigranulocyte antibodies); detection of myeloid bone marrow hyperplasia with a shift towards immature cellular elements. Ultrasound reveals a significant enlargement of the spleen. The article talks about the main points of the clinical picture and diagnostic criteria that make it possible to identify this syndrome and adjust the therapy of patients.
Full Text
##article.viewOnOriginalSite##About the authors
Vsevolod V. Skvortsov
FSBEI НЕ VolgSMU МОН Russia
Author for correspondence.
Email: vskvortsov1@ya.ru
Doctor of Medicine, Associate Professor of the Department of Internal Medicine
Russian Federation, VolgogradIrina V. Rodionova
FSBEI НЕ VolgSMU МОН Russia
Email: ivrodiolnova@volgmed.ru
Candidate of Medical Sciences, Associate Professor of the Department of Internal Medicine
Russian Federation, VolgogradMikhail A. Chudasov
FSBEI НЕ VolgSMU МОН Russia
Email: koteikafeda@gmail.com
4th year student
Russian Federation, VolgogradReferences
- Dwivedi N., Upadhyay J., Neeli I. et al. Felty’s syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps. Arthritis&Rheum. 2012; 64 (4): 982–992.
- Олюнин Ю.А. Синдром Фелти. Современная медицина. 2019; 13 (1): 145–148. [Oliunin Y.A. Felty’s syndrome. Sovremennaya medicina. 2019; 13 (1): 145–148.]
- Anupam Gupta Aryan Abrahimi & Aesha Patel Felty syndrome: a case report. Journal of Medical Case Reports. 2021; (15): 1–4.
- Введенский С.А., Халилова У.А., Скворцов В.В. и др. Cиндром Фелти. Медицинская сестра. 2019; 21 (7): 28–32. [Vvedensky S.A., Khalilova U.A., Skvortsov V.V. et al. Felty’s syndrome. Meditsinskaya sestra (The Nurse). 2019; 21 (7): 28–32.] https://doi.org/10.29296/25879979-2019-07-06
- Громова М.А., Мясоедова С.Е., Корягина Н.В. Синдром Фелти: особенности клинического течения и диагностики у больных ревматоидным артритом (клиническое наблюдение). Лечебное дело. 2017; (2): 84–87. [Gromova M.A., Myasoedova S.E. , Koryagina N.V. Felty’s syndrome: peculiarities of clinical course and diagnosis in patients with rheumatoid arthritis (clinical observation). The journal of General medicine. 2017; (2): 84–87.]
- Medlin J., Ishizawar R. Chapter 8: Felty’s Syndrome. In: Rare Rheumatic Diseases of Immunological Dysregulation. Ed: Teresa K. Tarrant; 2019.
- Муравьев Ю.В. Внесуставные проявления ревматоидного артрита. Научно-практическая ревматология. 2018; 56 (3): 356–362. [Muravyev Yu.V. Extra-articular manifestations of rheumatoid arthritis. Nauchno-Prakticheskaya Revmatologiya = Rheumatology Science and Practice. 2018; 56 (3): 356–362 (In Russ.)]. doi: 10.14412/1995-4484-2018-356-362
- Puksic S., Mitrovic J., Morovic-Vergles J. Rituximab: a safe treatment in a patient with refractory Felty syndrome and recurrent infections. J Clin Rheumatol. 2017; 23 (1): 70–71.
Supplementary files
