Targeted Bifunctional Proteins and Hybrid Nanoconstructs for Cancer Diagnostics and Therapies
- Autores: Deyev S.M.1,2, Lebedenko E.N.1
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Afiliações:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Lobachevsky State University of Nizhny Novgorod
- Edição: Volume 51, Nº 6 (2017)
- Páginas: 788-803
- Seção: Current Trends in the Application of Monoclonal Antibodies Special Issue
- URL: https://journal-vniispk.ru/0026-8933/article/view/163288
- DOI: https://doi.org/10.1134/S002689331706005X
- ID: 163288
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Resumo
In this review, the authors' works published within the past 5 years devoted to the development of bifunctional hybrid nanostructures based on the targeting polypeptides and nanoparticles of various origin (quantum dots, nanogold, nanodiamonds, upconversion nanoparticles, magnetic and polymer nanoparticles) as modules that ensure visualization and various damaging effects on cancer cells are surveyed and the prospects of their application in theranostics and precision medicine have been contemplated.
Sobre autores
S. Deyev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Lobachevsky State University of Nizhny Novgorod
Email: elebedenko@mail.ru
Rússia, Moscow, 117997; Nizhny Novgorod, 603950
E. Lebedenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Autor responsável pela correspondência
Email: elebedenko@mail.ru
Rússia, Moscow, 117997
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