Email this article Targeted Bifunctional Proteins and Hybrid Nanoconstructs for Cancer Diagnostics and Therapies
- Authors: Deyev S.M.1,2, Lebedenko E.N.1
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Affiliations:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Lobachevsky State University of Nizhny Novgorod
- Issue: Vol 51, No 6 (2017)
- Pages: 788-803
- Section: Current Trends in the Application of Monoclonal Antibodies Special Issue
- URL: https://journal-vniispk.ru/0026-8933/article/view/163288
- DOI: https://doi.org/10.1134/S002689331706005X
- ID: 163288
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Abstract
In this review, the authors' works published within the past 5 years devoted to the development of bifunctional hybrid nanostructures based on the targeting polypeptides and nanoparticles of various origin (quantum dots, nanogold, nanodiamonds, upconversion nanoparticles, magnetic and polymer nanoparticles) as modules that ensure visualization and various damaging effects on cancer cells are surveyed and the prospects of their application in theranostics and precision medicine have been contemplated.
About the authors
S. M. Deyev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Lobachevsky State University of Nizhny Novgorod
Email: elebedenko@mail.ru
Russian Federation, Moscow, 117997; Nizhny Novgorod, 603950
E. N. Lebedenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Author for correspondence.
Email: elebedenko@mail.ru
Russian Federation, Moscow, 117997
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