Отправить статью по E-mail HIV Restriction Factors and Their Ambiguous Role during Infection
- Авторы: Zotova A.A.1,2, Atemasova A.A.1, Filatov A.V.3, Mazurov D.V.2,3
-
Учреждения:
- Moscow State University, Faculty of Biology
- Cell and Gene Technology Group, Institute of Gene Biology, Russian Academy of Sciences
- National Research Center—Institute of Immunology of Federal Medical-Biological Agency of Russia
- Выпуск: Том 53, № 2 (2019)
- Страницы: 212-226
- Раздел: Reviews
- URL: https://journal-vniispk.ru/0026-8933/article/view/163862
- DOI: https://doi.org/10.1134/S0026893319020171
- ID: 163862
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
Currently, more than 37 million individuals worldwide are infected with the human immunodeficiency virus (HIV). Antiretroviral therapy may control the viral infection but is incapable of eradicating it. It is important to understand how cells respond to HIV-1 infection and what cellular factors are involved in this process to develop novel classes of antiviral drugs. This review summarizes the current understanding of the HIV restriction mechanism. We discuss the ambiguous role of HIV restriction factors in viral infection and counteraction mediated by HIV-1 accessory proteins.
Ключевые слова
Об авторах
A. Zotova
Moscow State University, Faculty of Biology; Cell and Gene Technology Group, Institute of Gene Biology, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: ashunaeva@gmail.com
Россия, Moscow, 119991; Moscow, 119334
A. Atemasova
Moscow State University, Faculty of Biology
Email: ashunaeva@gmail.com
Россия, Moscow, 119991
A. Filatov
National Research Center—Institute of Immunology of Federal Medical-Biological Agency of Russia
Email: ashunaeva@gmail.com
Россия, Moscow, 115478
D. Mazurov
Cell and Gene Technology Group, Institute of Gene Biology, Russian Academy of Sciences; National Research Center—Institute of Immunology of Federal Medical-Biological Agency of Russia
Email: ashunaeva@gmail.com
Россия, Moscow, 119334; Moscow, 115478
Дополнительные файлы
