Deferred Registration of Nanophosphor Photoluminescence As a Platform for Optical Bioimaging


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Detection systems with deferred registration of luminescence signals are promising for performing complex tasks of imaging of biological objects due to their simplicity and low cost. In the present work, β‑NaYF4:Tm3+Yb3+/NaYF4 nanocrystals with anti-Stokes photoluminescence have been used in deferred registration systems. It has been shown that there is a significant time delay between the exciting laser pulse and luminescence signal, which makes it possible to use this class of nanoparticles in the creation of wide-field imaging systems with deferred registration. The possibility of using nanoparticles for detecting a photoluminescence signal in the second transparency window of biotissue has been demonstrated. This system can be based on the resonance excitation and detection of the photoluminescence signal of Yb3+ ions.

作者简介

E. Khaydukov

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences; Sechenov First Moscow State Medical University

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333; Moscow, 119991

K. Boldyrev

Institute for Spectroscopy, Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, TroitskMoscow, 108840

K. Khaydukov

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333

I. Krylov

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333

I. Asharchuk

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333

A. Savelyev

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences; Sechenov First Moscow State Medical University

编辑信件的主要联系方式.
Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333; Moscow, 119991

V. Rocheva

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333

D. Karimov

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333

A. Nechaev

Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences; Institute for Spectroscopy, Russian Academy of Sciences

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119333; TroitskMoscow, 108840

A. Zvyagin

Sechenov First Moscow State Medical University; Moscow Technological University, Lomonosov Moscow State University of Fine Chemical Technologies; Macquarie University

Email: A.G.Savelyev@gmail.com
俄罗斯联邦, Moscow, 119991; Moscow, 119571; Sydney, North Ryde NSW, 2109

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