A Complex Study of the Peculiarities of Blood Serum Absorption of Rats with Experimental Liver Cancer


Дәйексөз келтіру

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Аннотация

Terahertz time-domain spectroscopy (THz-TDS) in the 0.05–1.0 THz frequency range was used to study the blood serum of rats in the dynamics of experimental liver cancer. It was shown that the THz transmission spectra of samples from healthy animals and 14 and 28 days after tumor cells implantation are similar in shape, but differ in amplitude. There is a change in the biochemical composition of the blood, including a decrease in the protein content, by the 28th day of the experiment. The observed changes in the THz response are explained by a decrease in the number of protein molecules and bound water and correlate with changes in the refractive index in the visible and near-IR ranges from 480 to 1550 nm, measured using a multiwave refractometer.

Авторлар туралы

M. Nazarov

National Research Centre Kurchatov Institute

Email: o.p.cherkasova@gmail.com
Ресей, Moscow, 123182

O. Cherkasova

Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences; Tomsk State University; Novosibirsk State Technical University

Хат алмасуға жауапты Автор.
Email: o.p.cherkasova@gmail.com
Ресей, Novosibirsk, 630090; Tomsk, 634050; Novosibirsk, 630073

E. Lazareva

Tomsk State University; Saratov State University

Email: o.p.cherkasova@gmail.com
Ресей, Tomsk, 634050; Saratov, 410012

A. Bucharskaya

Saratov State Medical University

Email: o.p.cherkasova@gmail.com
Ресей, Saratov, 410012

N. Navolokin

Saratov State Medical University

Email: o.p.cherkasova@gmail.com
Ресей, Saratov, 410012

V. Tuchin

Tomsk State University; Saratov State University; Institute of Precision Mechanics and Control, Russian Academy of Sciences

Email: o.p.cherkasova@gmail.com
Ресей, Tomsk, 634050; Saratov, 410012; Saratov, 410028

A. Shkurinov

Moscow State University; Institute for Problems of Laser and Information Technologies of the Russian Academy of Sciences,
Branch of Federal Scientific Research Center Crystallography and Photonics

Email: o.p.cherkasova@gmail.com
Ресей, Moscow, 119991; Shatura, 140700

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