Solubility of 2-Chloro-3-(trifluoromethyl)pyridine and Correlation with the Polarity in Organic Solvents at 273–303 K

Resumo

The solubility of 2-chloro-3-(trifluoromethyl)pyridine (CTP) in ethyl acetate, n-butyl alcohol, 2‑propanol, methanol, trichloromethane, acetonitrile, and acetone under atmospheric pressure was measured at 273.15–303.15 K. The solubility of CTP in all eight solvents increased with the increase in temperature. The solubility of CTP had a relation with the polarity of the solvents. The modified Apelblat equation, λh equation, Wilson model, and NRTL model were used to correlate the solubility. The standard dissolution enthalpies were also evaluated.