Email this article Significance of damage index in prediction of systemic lupus erythematosus outcome
- Authors: Tarasova IA1, Ivanova MM1, Zhornyak AP1, Nasonova VA1
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Affiliations:
- Институт ревматологии РАМН
- Issue: Vol 78, No 1 (2003)
- Pages: 59-62
- Section: Editorial
- URL: https://journal-vniispk.ru/0040-3660/article/view/29294
- ID: 29294
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Abstract
Aim. To determine the significance of the damage index (SLICC/ACR DI) in the prognosis of the outcome of systemic lupus erythematosus (SLE).
Materials and methods. Correlations between the disease activity, cumulative damage and outcome were studied in 103 patients with SLE divided into two groups by the disease duration (21 to 60 months - group 1, 62 to 488 months - group 2). SLE activity was determined by Nasonova's classification, SLEDAI-1 and ECLAM. Cumulative damage was assessed by the damage index (systemic lupus international collaborating clinics/'ACR damage index).
Results. We found the direct correlation between the age of the disease onset, SLE duration, degree of SLE activity and the damage index and between the maximal dose of glucocorticosteroids and the damage index. Conclusion. The results indicate that SLICC/ACR DI may be useful for outcome prediction in SLE.
Materials and methods. Correlations between the disease activity, cumulative damage and outcome were studied in 103 patients with SLE divided into two groups by the disease duration (21 to 60 months - group 1, 62 to 488 months - group 2). SLE activity was determined by Nasonova's classification, SLEDAI-1 and ECLAM. Cumulative damage was assessed by the damage index (systemic lupus international collaborating clinics/'ACR damage index).
Results. We found the direct correlation between the age of the disease onset, SLE duration, degree of SLE activity and the damage index and between the maximal dose of glucocorticosteroids and the damage index. Conclusion. The results indicate that SLICC/ACR DI may be useful for outcome prediction in SLE.
About the authors
I A Tarasova
Институт ревматологии РАМНМосква; Институт ревматологии РАМН
M M Ivanova
Институт ревматологии РАМНМосква; Институт ревматологии РАМН
A P Zhornyak
Институт ревматологии РАМНМосква; Институт ревматологии РАМН
V A Nasonova
Институт ревматологии РАМНМосква; Институт ревматологии РАМН
References
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