电邮这篇文章 Effects of recurrent herpetic infection on functional activity of T-cells in patients with rheumatoid arthritis
- 作者: Sviridova VS, Kologrivova EN, Pronina NA, Eliseeva LV, Naslednikova IO, Sviridova VS, Kologrivova EN, Pronina NA, Eliseeva LV, Naslednikova IO
- 期: 卷 81, 编号 6 (2009)
- 页面: 27-28
- 栏目: Editorial
- URL: https://journal-vniispk.ru/0040-3660/article/view/30345
- ID: 30345
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Material and methods. We studied in vitro production of marker cytokines of type 1 T-helpers (IL-2), type 2 T-helpers (IL-4), type 3 T-helpers TGFb and type 1 T-regulators (IL-10) and counted CD4+CD25+ T-cells in the blood of patients with recurrent herpetic infection and having no clinical manifestations of Herpes virus reactivation.
Results. Patients with recurrent herpes had more active production of IL-10, but reduced count of CD4+CD25+ lymphocytes.
Conclusion. IL-10 hyperproduction observed in recurrent herpetic infection may contribute to progression of rheumatoid arthritis.
作者简介
V Sviridova
E Kologrivova
N Pronina
L Eliseeva
I Naslednikova
V Sviridova
E Kologrivova
N Pronina
L Eliseeva
I Naslednikova
参考
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