Email this article Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2-D]Pyrimidine Derivatives
- Authors: Dashyan S.S.1, Paronikyan E.G.1, Noravyan A.S.1, Paronikyan R.G.1
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Affiliations:
- Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Issue: Vol 50, No 4 (2016)
- Pages: 221-225
- Section: Search for New Drugs
- URL: https://journal-vniispk.ru/0091-150X/article/view/244347
- DOI: https://doi.org/10.1007/s11094-016-1426-x
- ID: 244347
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Abstract
A method for preparing the amino, alkoxy, and alkylsulfanyl derivatives of pyrano[4″,3″:4′,5′]pyrido-[3′,2′:4,5]thieno[3,2-d]pyrimidines based on 8-chloro-2,2-dimethyl-5-pyrrolidin-1-yl-1,4-dihydro-2H-pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine was developed. The anticonvulsant activity of the compounds synthesized here was investigated.
About the authors
Sh. Sh. Dashyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Armenia, Yerevan
E. G. Paronikyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Armenia, Yerevan
A. S. Noravyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Armenia, Yerevan
R. G. Paronikyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Armenia, Yerevan
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