Отправить статью по E-mail Synthesis and Cytotoxic Activity of Arylsubstituted Tetrazolocyclanopyrimidines
- Авторы: Vasil’kova N.O.1, Ivonin M.A.1, Burygin G.L.2, Prilepskii A.Y.2, Kriven’ko A.P.1
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Учреждения:
- N. G. Chernyshevskii Saratov State National Research University
- Institute of Plant and Microbial Biochemistry and Physiology
- Выпуск: Том 51, № 9 (2017)
- Страницы: 756-759
- Раздел: The Search for New Drugs
- URL: https://journal-vniispk.ru/0091-150X/article/view/244789
- DOI: https://doi.org/10.1007/s11094-017-1687-z
- ID: 244789
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Аннотация
A series of arylsubstituted tetrazolocyclanodihydropyrimidines was prepared and their cytotoxic actions on SPEV-2 cells were studied. The activity of these substances was found to depend on the nature and position of the substitution groups in the benzene ring and the size of the alicycle. The most active compounds were o-chloro(methyl)phenyltetrazolohexahydroquinazolines.
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Об авторах
N. Vasil’kova
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
Россия, Saratov
M. Ivonin
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
Россия, Saratov
G. Burygin
Institute of Plant and Microbial Biochemistry and Physiology
Email: chem@folium.ru
Россия, Saratov
A. Prilepskii
Institute of Plant and Microbial Biochemistry and Physiology
Email: chem@folium.ru
Россия, Saratov
A. Kriven’ko
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
Россия, Saratov
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