R-Benzylidenehydrazides of NH-Furoyl-5-Iodoanthranilic Acids: Synthesis, Properties, and Analgesic and Antibacterial Activity

A. F. Gazizova; E. R. Kurbatov; R. R. Makhmudov; A. A. Bobyleva; L. M. Korkodinova; A. A. Kurbatova

doi:10.1007/s11094-019-01934-z

R-Benzylidenehydrazides of NH-Furoyl-5-Iodoanthranilic Acids: Synthesis, Properties, and Analgesic and Antibacterial Activity

Authors: Gazizova A.F.¹, Kurbatov E.R.¹, Makhmudov R.R.²^,3, Bobyleva A.A.¹, Korkodinova L.M.¹, Kurbatova A.A.¹
Affiliations:
1. Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
2. Perm State National Research University
3. Federal Scientific Center for Medical and Preventive Public Health Risk Management Technologies
Issue: Vol 52, No 12 (2019)
Pages: 965-968
Section: Search for New Drugs
URL: https://journal-vniispk.ru/0091-150X/article/view/245561
DOI: https://doi.org/10.1007/s11094-019-01934-z
ID: 245561

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Abstract

A series of R-benzylidenehydrazides of NH-furoyl-5-iodoanthranilic acid were synthesized by condensing NH-furoyl-5-iodoanthranilic acid hydrazide with aromatic aldehydes. Their structures were confirmed using IR and PMR spectroscopy. Their analgesic and antibacterial activities were studied.