New 3-(4-Propoxybenzyl)-5-Sulfanyl-Substituted (4H)-1,2,4-Triazoles and Their Antitumor Activity


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3,4-Substituted-(4H)-1,2,4-triazole-5-thiols were synthesized and used for S-alkylation, cyanoethylation, and aminomethylation to produce a series of new 1,2,4-triazole derivatives of interest as biologically active compounds. The antitumor properties of several of the 1,2,4-triazole derivatives were studied.

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T. Ovsepyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

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Email: tag.hovsepyan@mail.ru
亚美尼亚, 26 Azatutyan Prosp, Erevan, 0014

S. Dilanyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: tag.hovsepyan@mail.ru
亚美尼亚, 26 Azatutyan Prosp, Erevan, 0014

F. Arsenyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: tag.hovsepyan@mail.ru
亚美尼亚, 26 Azatutyan Prosp, Erevan, 0014

R. Muradyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: tag.hovsepyan@mail.ru
亚美尼亚, 26 Azatutyan Prosp, Erevan, 0014

N. Minasyan

Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: tag.hovsepyan@mail.ru
亚美尼亚, Erevan, 0014

R. Melik-Ohanjanyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: tag.hovsepyan@mail.ru
亚美尼亚, 26 Azatutyan Prosp, Erevan, 0014

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