Features of subgingival biofilm microbiota in adolescents with type 1 diabetes mellitus
- Авторлар: Shcherbakova М.M.1, Bochkalova Т.Y.2, Allahverdiev А.F.1, Levina I.S.1, Morozova N.S.1
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Мекемелер:
- I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
- Khimki Clinical Hospital
- Шығарылым: Том 36, № 1 (2025)
- Беттер: 62-65
- Бөлім: From Practice
- URL: https://journal-vniispk.ru/0236-3054/article/view/287223
- DOI: https://doi.org/10.29296/25877305-2025-01-12
- ID: 287223
Дәйексөз келтіру
Аннотация
Purpose. To study the composition of microbiota of subgingival biofilm using the GCMS method (according to Osipov).
Materials and methods. The study involved 30 patients with ICD-10 diagnosis E10 “Insulin-dependent diabetes mellitus” and 30 adolescents without general medical pathology (conditionally healthy children) aged 13 to 17. The condition of periodontal tissues was evaluated by periodontal indices: GI, PMA, SBI. Microbiota was evaluated by gas chromatography-mass spectrometry (CGMS) (according to Osipov).
Results. The SBI index in adolescents with type 1 diabetes mellitus (DM) was 2.15±0.09 scores, the index of the control group – 1.67±0.02 scores, GI index – 2.34±0.08 and 1.33±0.08 scores respectively, PMA index – 67.80±1.09 and 33.70±2.86% respectively. According to the results of CGMS analysis (according to Osipov), a statistically significant increase in the indices in patients with type 1 DM was observed in microorganisms: Actinomyces spp., Eubacterium spp., Moraxella spp., Prevotella spp., Staphilococcus aureus, Bacteroides spp. and yeast-like fungi (Candida albicans).
Conclusion. The results obtained indicate an increase in periodontopathogenic microbiota in the subgingival biofilm in adolescent patients with type 1 DM.
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##article.viewOnOriginalSite##Авторлар туралы
М. Shcherbakova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Хат алмасуға жауапты Автор.
Email: marya.scherbakova@yandex.ru
ORCID iD: 0009-0006-1816-7839
Ресей
Т. Bochkalova
Khimki Clinical Hospital
Email: marya.scherbakova@yandex.ru
ORCID iD: 0009-0008-7392-5625
Ресей, Khimki
А. Allahverdiev
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: marya.scherbakova@yandex.ru
Ресей
I. Levina
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: marya.scherbakova@yandex.ru
Ресей
N. Morozova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: marya.scherbakova@yandex.ru
ORCID iD: 0000-0002-6453-1615
Professor, MD
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