DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE

D. K. Lvov; Львов Д. К.; E. I. Burtseva; Бурцева Е. И.; E. S. Kirillova; Кириллова Е. С.; L. V. Kolobukhina; Колобухина Л. В.; E. A. Mukasheva; Мукашева Е. А.; S. V. Trushakova; Трушакова С. В.; E. L. Feodoritova; Феодоритова Е. Л.; L. N. Merkulova; Меркулова Л. Н.; K. G. Krasnoslobodtsev; Краснослободцев К. Г.; E. O. Garina; Гарина Е. О.; I. T. Fedyakina; Федякина И. Т.; V. A. Aristova; Аристова В. А.; R. V. Vartanyan; Вартанян Р. В.; L. B. Kisteneva; Кистенёва Л. Б.; P. G. Deryabin; Дерябин П. Г.; A. G. Prilipov; Прилипов А. Г.; A. G. Rosatkevich; Росаткевич А. Г.; N. V. Breslav; Бреслав Н. В.; I. S. Kruzhkova; Кружкова И. С.; A. L. Belyaev; Беляев А. Л.; E. V. Aksel’Rod; Аксельрод Э. В.; G. K. Sadykova; Садыкова Г. К.; O. V. Shlyapnikova; Шляпникова О. В.; M. V. Bazarova; Базарова М. В.; A. V. Devyatkin; Девяткин А. В.

doi:10.18821/0507-4088-2018-63-2-61-68

DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE

Authors: Lvov D.K.¹, Burtseva E.I.¹, Kirillova E.S.¹, Kolobukhina L.V.¹, Mukasheva E.A.¹, Trushakova S.V.¹, Feodoritova E.L.¹, Merkulova L.N.¹, Krasnoslobodtsev K.G.¹, Garina E.O.¹, Fedyakina I.T.¹, Aristova V.A.¹, Vartanyan R.V.¹, Kisteneva L.B.¹, Deryabin P.G.¹, Prilipov A.G.¹, Rosatkevich A.G.¹, Breslav N.V.¹, Kruzhkova I.S.¹, Belyaev A.L.¹, Aksel’Rod E.V.¹, Sadykova G.K.¹, Shlyapnikova O.V.¹, Bazarova M.V.², Devyatkin A.V.²
Affiliations:
1. D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»
2. Clinical Hospital for Infectious Diseases No. 1
Issue: Vol 63, No 2 (2018)
Pages: 61-68
Section: ORIGINAL RESEARCH
URL: https://journal-vniispk.ru/0507-4088/article/view/117956
DOI: https://doi.org/10.18821/0507-4088-2018-63-2-61-68
ID: 117956

Cite item

Full Text

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

The article presents the features of the influenza virus circulation for the period from October 2016 to May 2017 in some territories of Russia collaborating with the D.I. Ivanovsky Institute of Virology, Federal State Budgetary Institution “N.F. Gamaleya Federal Research Centre for Epidemiology and Microbiology”, Ministry of Health of the Russian Federation. One of the 2016-2017 season’s peculiarities in Russia and countries of the Northern hemisphere was the earlier start of an increase in ARD morbidity with peak indexes reached towards the end of December 2016 - January 2017. First, influenza A(H3N2) virus was predominant; then, it was followed by influenza B virus activity observed until the end of the season. The indexes of morbidity were higher than in the previous season, while the rates of hospitalization and mortality were lower, lethal cases being detected in persons 65 years old and older. Epidemic strains of influenza A(H3N2) virus belonged to 3c.2a genetic group, reference strain A/Hong Hong/4408/2014, and its subgroup 3c.2a1, reference A/Bolzano/7/2016, that are antigenically similar. Strains of influenza B virus were antigenically similar to the B/Brisbane/60/2008 vaccine virus. Strains were sensitive to oseltamivir and zanamivir. The share participation of non-influenza ARI viruses was similar to preliminary epidemic seasons. WHO has issued recommendations for influenza virus vaccines composition for 2017-2018 for the Northern hemisphere.

Keywords

epidemic season 2016-2017, influenza A(H3N2) virus, antigenic properties, genetic properties, susceptibility to anti-neuraminidase inhibitors, influenza virus vaccines composition 2017-2018 for the Northern hemisphere

References

Литвинова О.М., Смородинцева Е.А., Деева Э.Г., Лобова Т.Г., Коновалова Н.И. Этиология современного гриппа. В кн.: Киселев О.И., Маринич И.Г., Сомнина А.А. Грипп и другие респираторные инфекции: эпидемиология, профилактика, диагностика и терапия. СПб.: Боргес; 2003: 55-69.
Львов Д.К., Бурцева Е.И., Колобухина Л.В., Дерябин П.Г., Кириллова Е.С., Трушакова С.В. и др. Особенности эпидемического сезона 2014/2015 гг. по гриппу в разных регионах России. Инфекционные болезни. 2015; 13(4): 59-67.
Skowronski D., Chambers C., Sabaiduc S., Serres G. De., Dickinson J.A., Winter A.L., et al. Interim estimates of 2014/2015 vaccine effectiveness against influenza A(H3N2) from Canada’s Sentinel Physician Surveillance network, January 2015. Euro Surveill. 2015; 20(4).
Pebody R., Warburton F., Ellis J., Andrews N., Thompson C., von Wissmann B., et al. Low effectiveness of seasonal influenza vaccine in preventing laboratory confirmed influenza in primary care in the United Kingdom: 2014/2015 mid-season results. Euro Surveill. 2015; 20(5).
Мatrosovich M., Matrosovich T., Carr G., Roberts N.A., H.-D.Klenk. Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors. J. Virol. 2003; 77(15): 8418-25.
WHO Global Influenza Surveillance Network. Manual for the laboratory diagnosis and virological surveillance of influenza. Available at: http://www.who.int/influenza/gisrs_laboratory/manual_diagnosis_surveillance_influenza/en/
МР N.0100/4430-06-34. Выделение вирусов гриппа в клеточных культурах и куриных эмбрионах и их идентификация. М.; 2006.
Бурцева Е.И., Бреслав Н.В., Кириллова Е.С., Колобухина Л.В., Прилипов А.Г., Малышев Н.А. и др. Ингибиторы нейраминидазы вирусов гриппа: эффективность в постпандемический период. Эффективная фармакотерапия. 2016; 44(2): 32-6.
Review of global influenza activity, 2015-2016. Available at: http://www.who.int/influenza/surveillance_monitoring/updates/en/
Global circulation of influenza viruses (GISRS-FluNet, snapshot 24 November 2017). Available at: http://www.who.int/influenza/gisrs_laboratory/updates/summaryreport/en/
A weekly influenza surveillance report prepared by the Influenza Division, CDC, Atlanta, USA (FluView). Available at: http://www.cdc.gov/flu/weekly/index.htm
Joint ECDC-WHO/Europe weekly influenza updates. Available at: http://www.flunewseurope.org/
Сайт ФГБУ «НИИ гриппа» Минздрава России. Available at: http://www.influenza.spb.ru
Weekly Epidemiological Record. 2017; 92(11): 117-28. Available at: http://www.who.int/wer/2017/wer9211/en/
Данные по случаям инфицирования людей вирусами гриппа птиц и свиней. Available at: http://www.who.int/influenza/human_animal_interface/ru/
Случаи инфицирования людей вирусом гриппа птиц A(H7N9). Available at: http://who.int/influenza/human_animal_interface/influenza_h7n9/ru/index.html.
Cumulative number of confirmed human cases of avian influenza A(H5N1) reported to WHO. Available at: http://www.who.int/influenza/human_animal_interface/H5N1_cumulative_table_archives/en/
Assessment of risk associated with influenza A(H5N8) virus. Available at: http://www.who.int/influenza/human_animal_interface/avian_influenza/riskassessment_AH5N8_201611/en/

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE

Full Text

Abstract

Keywords

About the authors

References

Supplementary files