Human cytomegalovirus infection and spontaneous abortion in pregnant women of I and II trimester
- Authors: Cheshik S.G.1, Kisteneva L.B.1
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Affiliations:
- Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
- Issue: Vol 61, No 2 (2016)
- Pages: 74-78
- Section: ORIGINAL RESEARCH
- URL: https://journal-vniispk.ru/0507-4088/article/view/118055
- DOI: https://doi.org/10.18821/0507-4088-2016-61-2-74-78
- ID: 118055
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Abstract
The goal of this work was the evaluation of the frequency of human CMV infection among the women, whose pregnancy ended in miscarriage, detection of active forms of infection and treatment before pregnancy. Virological and sero-immunological techniques were used. A total of 116 women who had miscarriages before the 28 week of pregnancy were submitted to the CMV test. 109 women (94.0%) demonstrated positive results. 49 women (42.2%) had active form of the cytomegalovirus infection. 13 women (26.5%) had the recurrent form and 36 patients (73.5%) had the persistent form of CMV infection (stage of productive replication). All the women with active cMVi were treated before the next pregnancy. Immunomodulatory therapy for the treatment was used.
About the authors
S. G. Cheshik
Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
Email: fake@neicon.ru
ORCID iD: 0000-0001-7639-7268
Moscow, 123098 Russian Federation
L. B. Kisteneva
Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
Author for correspondence.
Email: lidia.kisteneva@gmail.com
ORCID iD: 0000-0001-7336-409X
Lidia B. Kisteneva, Doctor of Medicine, Head of the Laboratory of epidemiology, prevention and diagnosis of viral hepatitis
Moscow, 123098
Russian FederationReferences
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