Study of the prevalence of antibodies to some arboviruses in the population of the Republic of Guinea
- 作者: Naidenova E.V.1, Kartashov M.Y.2, Zakharov K.S.1, Shevtsova A.P.1, Diallo M.G.3, Nourdine I.4, Bah M.B.4, Boumbaly S.4, Shcherbakova S.A.1, Kutyrev V.V.1
-
隶属关系:
- FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
- FSBI State Scientific Center of Virology and Biotechnology «Vector» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
- Regional University of Kindia
- Research Institute of Applied Biology of Guinea
- 期: 卷 66, 编号 5 (2021)
- 页面: 346-353
- 栏目: ORIGINAL RESEARCH
- URL: https://journal-vniispk.ru/0507-4088/article/view/118171
- DOI: https://doi.org/10.36233/0507-4088-74
- ID: 118171
如何引用文章
详细
Introduction. Acute febrile diseases kill more than 250,000 people annually in West Africa. Malaria and typhoid fever traditionally occupy most of the total structure of registered fevers. However, these data do not fully reflect the true overall disease patterns in the West African region. This is due to the fact that diagnosis is mainly based on the clinical signs of the infectious process, suggesting that a certain number of diseases may be caused by arboviruses. The detection of specific antibodies (ABs) to infectious pathogens in the blood sera of residents of a particular area is a reliable indicator of the circulation of these pathogens in a particular territory.
The aim of this study was to determine the prevalence of antibodies to a number of arboviruses: Dengue (DENV), West Nile (WNV) (family Flaviviridae), Crimean-Congo hemorrhagic fever (orthonairo)virus (CCHFV), Batai (Batai virus), Bhanja (BHAV) (order Bunyavirales), Chikungunya (CHIKV), and Sindbis (SINV) (family Togaviridae) in the population of the Republic of Guinea.
Material and methods. In total, a panel of 2,620 blood serum samples from people living in all landscape and geographical areas of Guinea was collected for the study. Detection of IgG antibodies was performed using an enzyme-linked immunoassay (ELISA).
Results. In total, ABs to Batai virus were detected in 144 samples (5.5%), BHAV in 58 (2.2%), WNV in 892 (34.0 %), DENV in 659 (25.2 %), CCHFV in 58 (2.2 %), CHIKV in 339 (12.9 %), and SINV in 52 samples (2.0 %).
Discussion. The obtained results indicate serological evidence of the spectrum of arboviruses in the population of all landscape and geographical zones of the Republic of Guinea, confirming their active circulation in this territory.
Conclusion. Given the high epidemiological significance of arbovirus infectious diseases, it is an urgent task to continue studying its share in the structure of febrile diseases in the territory of the Republic of Guinea.
作者简介
E. Naidenova
FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
编辑信件的主要联系方式.
Email: katim2003@mail.ru
ORCID iD: 0000-0001-6474-3696
Ekaterina V. Naidenova, Ph.D. (Biol.), Lead Researcher of the Virology Laboratory of the Infectious Diseases Diagnostic Department
410005, Saratov, Russia
俄罗斯联邦M. Kartashov
FSBI State Scientific Center of Virology and Biotechnology «Vector» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
Email: fake@neicon.ru
ORCID iD: 0000-0002-7857-6822
630559, Novosibirsk Region, Kol’tsovo, Russia
俄罗斯联邦K. Zakharov
FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
Email: fake@neicon.ru
ORCID iD: 0000-0002-4726-309X
410005, Saratov, Russia
俄罗斯联邦A. Shevtsova
FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
Email: fake@neicon.ru
ORCID iD: 0000-0001-9600-3801
410005, Saratov, Russia
俄罗斯联邦M. Diallo
Regional University of Kindia
Email: fake@neicon.ru
ORCID iD: 0000-0003-4507-4575
Kindia, Republic of Guinea
几内亚I. Nourdine
Research Institute of Applied Biology of Guinea
Email: fake@neicon.ru
ORCID iD: 0000-0002-2970-9676
Kindia, Republic of Guinea
几内亚M. Bah
Research Institute of Applied Biology of Guinea
Email: fake@neicon.ru
ORCID iD: 0000-0002-4565-269X
Kindia, Republic of Guinea
俄罗斯联邦S. Boumbaly
Research Institute of Applied Biology of Guinea
Email: fake@neicon.ru
ORCID iD: 0000-0002-4506-6033
Kindia, Republic of Guinea
几内亚S. Shcherbakova
FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
Email: fake@neicon.ru
ORCID iD: 0000-0003-1143-4069
410005, Saratov, Russia
俄罗斯联邦V. Kutyrev
FSHI Russian Research Anti-Plague Institute «Microbe» of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)
Email: fake@neicon.ru
ORCID iD: 0000-0003-3788-3452
410005, Saratov, Russia
俄罗斯联邦参考
- ВОЗ. Болезнь, вызванная вирусом Эбола. Available at: http://www.who.int/mediacentre/factsheets/fs103/ru/ (accessed October 4, 2021).
- Park S.E., Pak G.D., Aaby P., Adu-Sarkodie Y., Ali M., Aseffa A., et al. The relationship between invasive nontyphoidal Salmonella disease, other bacterial bloodstream infections, and Malaria in Sub-Saharan Africa. Clin. Infect. Dis. 2016; 62(Suppl. 1): S.23–31. https://doi.org/10.1093/cid/civ893
- Schoepp R.J., Rossi C.A., Khan S.H., Goba A., Fair J.N. Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg. Infect. Dis. 2014; 20(7): 1176–82. https://doi.org/10.3201/eid2007.131265
- Jentes E.S., Robinson J., Johnson B.W., Conde I., Sakouvougui Y., Iverson J., et al. Acute arboviral infections in Guinea, West Africa, 2006. Am. J. Trop. Med. Hyg. 2010; 83(2): 388–94. https://doi.org/10.4269/ajtmh.2010.09-0688
- Countrymeters. Население Гвинеи. Available at: https://countrymeters.info/ru/guinea (accessed October 4, 2021).
- Черч Гаррисон Р.Д. Западная Африка. Природная среда и ее хозяйственное использование. М.: Изд-во иностр. лит.; 1959.
- Бутенко А.М. Изучение циркуляции арбовирусов в Гвинейской Республике. Медицинская паразитология и паразитарные болезни. 1996; 2: 40–5.
- Константинов О.К., Диалло С.М., Инапоги А.П., Ба А., Камара С.К. Млекопитающие Гвинеи как резервуары и носители арбовирусов. Медицинская паразитология и паразитарные болезни. 2006; (1): 34–9.
- Титенко А.М. Факторы, способствующие появлению и обнаружению новых вирусных инфекций. Эпидемиология и инфекционные болезни. 2004; (1): 51–5.
- Найденова Е.В., Пьянков С.А., Крицкий А.А., Касьян Ж.А., Раздорский А.С., Лопатин А.А., и др. Выявление специфических антител к арбовирусам в сыворотках крови людей, проживающих в провинции Киндиа, Гвинейская Республика. Проблемы особо опасных инфекций. 2016; (3): 62–5. https://doi.org/10.21055/0370-1069-2016-3-62-65
- Naidenova E.V., Zakharov K.S., Agafonov D.A., Senichkina A.M., Shcherbakova S.A., Kutyrev V.V., et al. Prevalence of Crimean-Congo hemorrhagic fever virus in rural areas of Guinea. Ticks Tick Borne Dis. 2020; 11(5): 101475. https://doi.org/10.1016/j.ttbdis.2020.101475
- Найденова Е.В., Лопатин А.А., Сафронов В.А., Коломоец Е.В., Левковский А.Е., Силла А.Л., и др. Обеспечение биологической безопасности при проведении противоэпидемических мероприятий в период ликвидации эпидемии лихорадки Эбола в Гвинейской Республике. Инфекционные болезни: новости, мнения, обучение. 2018; 7(3): 102–8. https://doi.org/10.24411/2305-3496-2018-13015
- PEDro. Confidence interval calculator. Available at: https://pedro.org.au/english/resources/confidence-interval-calculator (accessed October 4, 2021).
补充文件
