Cyclization of ethyl [cyano(4,6-dimethylpyrimidin-2-yl)amino]-acetate

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Imidazolin-4-one derivatives have been prepared by a reaction of ethyl [cyano(4,6-dimethylpyrimidin-2-yl)amino]acetate (2) with morpholine, piperidine and hydrazides. In the presence of sulfuric acid, cyanoester 2 gives 2-iminooxazolin-5-one which is acylated on the nitrogen atom of imino group and is rearranged to imidzolidin-2,4-dione in the presence of KCNO.

Sobre autores

A. Shiryaev

Samara State Technical University

Email: shiryaev.ak@samgtu.ru
Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

M. Krasavina

Samara State Technical University

Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

V. Shiryaev

Samara State Technical University

Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

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