Correction of vascular, thrombocytic and coagulative system of homeostasis in trauma and orthopaedic microsurgery

N. P. Mironov; Миронов Н. П.; V. A. Svetlov; Светлов В. А.; A. V. Vabishchevich; Вабищевич А. В.; A. I. Krupatkin; Крупаткин А. И.; S. A. Fedotov; Федотов С. А.

doi:10.17816/vto104850

Correction of vascular, thrombocytic and coagulative system of homeostasis in trauma and orthopaedic microsurgery

Authors: Mironov N.P.¹^,2^,3, Svetlov V.A.¹^,2^,3, Vabishchevich A.V.¹^,2^,3, Krupatkin A.I.¹^,2^,3, Fedotov S.A.¹^,2^,3
Affiliations:
1. Priorov Central Institute of Traumatology and Orthopedics
2. Scientific Center for Surgery
3. Medical Center of the Presidential Administration of the Russian Federation
Issue: Vol 5, No 4 (1998)
Pages: 36-40
Section: Articles
URL: https://journal-vniispk.ru/0869-8678/article/view/104850
DOI: https://doi.org/10.17816/vto104850
ID: 104850

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Abstract

To improve the blood circulation during reconstructive operations with microsurgical technique acelysin (1.92±0.19 mg/kg) and clexane (0.59±0.07 mg/kg) was applied intra- and postoperatively in 16 and 11 patients, respectively. Control group included 12 patients. The study of coagulative, vascular and thrombocytic systems showed that the drugs were effective to keep up moderate blood hypocoagulation during and after long microsurgical operations. Acelysin provided prolonged hypocoagulation state while clexane had less prolonged and more slight effect.