Magnetic Resonance Imaging of the Whole Body (DWIBS). Potentialities and Perspectives for Application in Bone Pathology


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Abstract

The purpose of the study was to determine the role and place of whole body MRI with DWIBS in diagnosis of human loco-motor system oncologic pathology. Two hundred fifty six patients with presumptive diagnosis of oncologic disease were examined. Obtained signal was evaluated by true signal intensity scale in minimal examination volume (voxel), either drawn through the volumetric lesion or in an isolated area of arbitrary shape. Study results were verified using standard MRI protocols (T1, T2, STIR), contrast enhancement, MSCT, radionuclide and morphologic examination. High sensitivity of the technique to pathologically changed tissues with reduced water diffusion coefficient was demonstrated. Magnetic resonance diffusion-weighted whole-body imaging with DWIBS may be recommended as noninvasive screening technique for the diagnosis of both primary and secondary (metastases) oncologic process.

About the authors

A. K Morozov

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov

доктор мед. наук, зав. отделением лучевой диагностики ЦИТО

A. N Makhson

City Oncologic Hospital №62, Moscow, Russia

доктор мед. наук, профессор, главврач МГОБ №62

I. N Karpov

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov

Email: igorkarpoff@mail.ru
канд. мед. наук, старший науч. сотр. отделения лучевой диагностики ЦИТО; Тел.: +7 (916) 611-97-58. 127299, Москва, ул. Приорова, д. 10, ЦИТО

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