Email this article Clinical use of bisphosphonates
- Authors: Rodionova S.S.1,2, Yuryeva E.A.1,2, Kolondaev А.F.1,2, Mashkovskaya T.А.1,2
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Affiliations:
- Central Institute of Traumatology and Orthopedics. N.N. Priorov
- Institute of Pediatrics and Pediatric Surgery
- Issue: Vol 6, No 1 (1999)
- Pages: 61-65
- Section: Reviews, literature review
- URL: https://journal-vniispk.ru/0869-8678/article/view/98442
- DOI: https://doi.org/10.17816/vto98442
- ID: 98442
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Abstract
In the treatment of bone tissue pathology associated with a violation of its metabolism, drugs belonging to the class of bisphosphonates have been increasingly used in the last decade. Bisphosphonates are synthetic analogs of pyrophosphoric acid containing, instead of the chemical bond [P-O-P], which undergoes rapid decay in the body, a non-hydrolyzable bond [P-C-P]. This prevents the drugs from breaking down when taken per os, but since they are chelators, it is recommended to take them on an empty stomach to prevent binding to divalent ions.
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##article.viewOnOriginalSite##About the authors
S. S. Rodionova
Central Institute of Traumatology and Orthopedics. N.N. Priorov; Institute of Pediatrics and Pediatric Surgery
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
E. A. Yuryeva
Central Institute of Traumatology and Orthopedics. N.N. Priorov; Institute of Pediatrics and Pediatric Surgery
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
А. F. Kolondaev
Central Institute of Traumatology and Orthopedics. N.N. Priorov; Institute of Pediatrics and Pediatric Surgery
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
T. А. Mashkovskaya
Central Institute of Traumatology and Orthopedics. N.N. Priorov; Institute of Pediatrics and Pediatric Surgery
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
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