Electro-deposition of gold nanostructures on carbon paste electrode: a platform with signal amplification for voltammetric study and determination of pyridoxine (vitamin B6)

Abstract

For the first time, the electrochemical synthesis of gold nanostructures was done at the surface of carbon paste electrode. This device was used as a simple and sensitive electrochemical sensor for measurement of pyridoxine (Vitamin B₆, VB₆). The diffusion coefficient (D) and the kinetic parameters such as electron transfer coefficient (α) and catalytic rate constant (k) for VB₆ were also determined using electrochemical approaches. The cyclic voltammetry method showed VB₆ oxidation reaction with irreversible characteristics was diffusion-controlled at low scan rates. Using differential pulse voltammetry (DPV), the peak current was linearly dependent on VB₆ concentration in the ranges of 1.9–110.8 and 110.8–257.0 μM, with detection limit of 74.0 nM, respectively. Results showed there is no interference of other vitamins in oxidation of VB₆. DPV was used to quantify of VB₆ in some real samples by the standard addition method. The modified electrode showed good sensitivity and stability.