Email this article NEUROPSYCHIATRIC DISORDERS: DISTURBANCES OF REGULATORY FUNCTIONS AND FRONTAL-SUBCORTICAL CIRCUITS
- Authors: Damulin I.V1, Sivolap Y.P1
-
Affiliations:
- Sechenov First Moscow State Medical University
- Issue: Vol XLVII, No 4 (2015)
- Pages: 78-82
- Section: Articles
- URL: https://journal-vniispk.ru/1027-4898/article/view/13966
- DOI: https://doi.org/10.17816/nb13966
- ID: 13966
Cite item
Open Access
Access granted
Subscription Access
Abstract
The disturbances caused by disconnection of the frontal cortex and other brain regions including lesion of regulatory functions are considered. It is emphasized that lateral prefrontal cortex plays especial role in cognitive processes. Impaired connection beginning in the lateral prefrontal cortex leads to cognitive and behavioral disorders. Neuropsychiatric disorders due to orbitofrontal and anterior cingulate circle are descripted. The links/circuits between the basal ganglia and the cerebral cortex of the brain, providing implementation of a motor, cognitive, emotional and behavioral functions, is not limited to these areas, and is not exclusive to the front of the brain. There are circles between other sections of the brain and basal ganglia, providing perception involved in decision-making on the basis of incoming information to the brain of different modalities.
Full Text
##article.viewOnOriginalSite##About the authors
Igor V Damulin
Sechenov First Moscow State Medical University
Email: damulin@mmascience.ru
Department of Neurology and Neurosurgery 119991, Моscow, Тrubetsoi str., 8, building 2
Yury P Sivolap
Sechenov First Moscow State Medical University
Email: yura-sivolap@yandex.ru
Department of Psychiatry and Addictive Medicine 119991, Моscow, Тrubetsoi str., 8, building 2
References
- Alexander M.P., Stuss D.T. Disorders of frontal lobe functioning // Sem. Neurol. 2000. Vol. 20 (40). P. 427-437.
- Alvarez J.A., Emory E. Executive function and the frontal lobes: a meta-analytic review // Neuropsychol. Rev. 2006. Vol. 16 (1). P. 17-42.
- Cummings J.L. Frontal-subcortical circuits and human behavior // Arch. Neurol. 1993. Vol. 50. P. 873-880.
- Jurado M.B., Rosselli M. The elusive nature of executive functions: a review of our current understanding // Neuropsychol. Rev. 2007. Vol. 17. P. 213-233.
- Arango-Lasprilla J.C., Rogers H., Lengenfelder J. et al. Cortical and subcortical diseases: Do true neuropsychological differences exist? // Arch. Clin. Neuropsychol. 2006. Vol. 21. P. 29-40.
- Raj A., Kuceyeski A., Weiner M. A network diffusion model of disease progression in dementia // Neuron. 2012. Vol. 73. P. 1204-1215.
- Giovannetti T., Lamar M., Cloud B.S. et al. Different underlying mechanisms for deficits in concept formation in dementia // Arch. Clin. Neuropsychol. 2001. Vol. 16. P. 547-560.
- Sporns O. Networks of the Brain. Cambridge, London: The MIT Press, 2011. 412 p.
- Taylor M.A. The Fundamentals of Clinical Neuropsychiatry. New York, Oxford: Oxford University Press, 1999. 513 p.
- Haber S., McFarland N.R. The place of the thalamus in frontal cortical-basal ganglia circuits // The Neuroscientist. 2001. Vol. 7(4). P. 315-324.
- Knight R.T., D’Esposito M. Lateral prefrontal syndrome: a disorder of executive control. In: Neurological Foundations of Cognitive Neuroscience. Ed. by M.D’Esposito. Chapter 11. Cambridge, London: The MIT Press, 2003. 290 p.
- Shallice T. Theory of ‘mind’ and the prefrontal cortex // Brain. 2001. Vol. 124(2). P. 247-248.
- Nauta W.J.H. The problem of the frontal lobe: a reinterpretation // J. Psychiatr. Res. 1971. Vol. 8. P. 167-187.
- Kaufer D.I., Cummings J.L., Christine D. Effect of tacrine on behavioral symptoms in Alzheimer’s disease: an open-label study // J. Geriatr. Psychiatry Neurol. 1996. Vol. 9. P. 1-6.
- Nachev P. Cognition and medial frontal cortex in health and disease // Curr. Opin. Neurol. 2006. Vol. 19. P. 586-592.
- Della Sala S., Gray C., Spinnler H., Trivelly C. Frontal lobe function in man: the riddle revisited // Arch. Clin. Neuropsychol. 1998. Vol. 13(8). P. 663-682.
- Ricciardi E., Pietrini P. New light from the dark: what blindness can teach us about brain function // Curr. Opin. Neurol. 2011. Vol. 24. P. 357-363.
- Grossberg S. How does the cerebral cortex work? Development, learning, attention, and 3-D vision by laminar circuits of visual cortex // Behav. Cogn. Neurosci. Rev. 2003. Vol. 2(1). P. 47-76.
- van Spronsen M., Hoogenraad C.C. Synapse pathology in psychiatric and neurologic disease // Curr. Neurol. Neurosci. Rep. 2010. Vol. 10. P. 207-214.
Supplementary files
