IMMUNORABILITATION IN CHRONIC ISCHEMIA OF THE BRAIN
- 作者: Bystrova N.A.1, Shulginova A.A.1, Sunyaykina O.A.1, Mashoshina D.O.1
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隶属关系:
- Kursk State Medical University
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 177-179
- 栏目: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/1028-7221/article/view/119483
- DOI: https://doi.org/10.31857/S102872210006444-3
- ID: 119483
如何引用文章
全文:
详细
We examined 26 patients of the neurological department of the BMU “Kursk Regional Clinical Hospital” with chronic cerebral ischemia stage II against the background of hypertensive disease stage II. All were divided equally by random randomization and within two weeks received a comprehensive basic pharmacological therapy (enalapril, vinpocetine, ceraxon and mexicor). Half of the patients additionally received polyoxidonium. Immune disorders were assessed by indicators in the peripheral blood of the functional metabolic activity of neutrophils, plasma levels of cytokines, complement components and their inhibitors. Prior to treatment, violations indicating the presence of immune infl ammation were identifi ed. Inclusion of polyoxidonium into the complex pharmacotherapy eff ectively corrects the altered immune status parameters.
作者简介
N. Bystrova
Kursk State Medical University
编辑信件的主要联系方式.
Email: nabistrova@gmail.com
Doctor of Medicine, Professor, Department of Biochemistry,
Kursk
俄罗斯联邦A. Shulginova
Kursk State Medical University
Email: fake@neicon.ru
PhD in Medicine, Assistant of the Department of Neurology and Neurosurgery,
Kursk
俄罗斯联邦O. Sunyaykina
Kursk State Medical University
Email: fake@neicon.ru
PhD in Medicine, Associate Professor, Department of Biochemistry,
Kursk
俄罗斯联邦D. Mashoshina
Kursk State Medical University
Email: fake@neicon.ru
5th year student of the medical faculty,
Kursk
俄罗斯联邦参考
- Гаврилюк Е. В., Конопля А. И., Караулов А. В. Роль иммунных нарушений в патогенезе артериальной гипертонии. Иммунология. 2016, 37(1), 29–35.
- Гусев Е. И., Чуканова А. С. Современные патогенетические аспекты формирования хронической ишемии мозга. Журнал неврологии и психиатрии. 2015, 115(3), 4–8.
- Конопля А. И., Ласков В. Б., Шульгинова А. А. Иммунные и оксидантные нарушения у больных хронической ишемией мозга и их коррекция. Журнал неврологии и психиатрии. 2015, 115(11), 28–32.
- Неврология: национальное руководство. / Под ред. Боголепова А. Н., Мартынов М. Ю. ГЭОТАРМедиа, Москва 2018. том 1 (2-е издание, перер. и доп.), 880.
- Шульгинова А. А., Конопля А. И., Быстрова Н. А., Гаврилюк В. П., Караулов А. В. Коррекция иммунных нарушений при хронической ишемии головного мозга. Медицинская иммунология. 2018, 20(3), 401–410.
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