EVALUATION OF THE SYSTEM OF HEMOSTASIS AND FUNCTIONAL ACTIVITY OF NEUTROPHILS IN PATIENTS WITH ATHEROSCLEROSIS OF UNPAIRED VISCERAL BRANCHES OF THE ABDOMINAL AORTA AND TYPE 2 DIABETES MELLITUS

Aim. To study the features of the system of hemostasis and the functional activity of neutrophils in patients with atherosclerosis of unpaired visceral branches of the abdominal aorta, depending on the presence of type 2 diabetes. Methods. The study included 87 patients. The first group included 32 patients with atherosclerosis of vessels of the plannonic pool and type 2 diabetes, to the second group of 55 patients without type 2 diabetes. Results. The median activity of Wf in the group of patients with type 2 diabetes was 193,5 %, significantly exceeding the parameters of the second group of patients 160,0 %, (p = 0,002). The phagocytic number of neutrophils of the group of patients with type 2 diabetes significantly exceeded the similar index of the second group of patients (p = 0,01). Рositive correlation was found between the activity of von Wf and the intensity of phagocytosis of peripheral blood neutrophils (r =0,723; p=0,04), and phagocytic number (r=,771, p=0,025). Conclusion. In patients with atherosclerosis of the visceral branches of the abdominal aorta and type 2 diabetes, higher values of the phagocytic number of peripheral blood neutrophils and Wf activity were revealed.

фактор Виллебранда, нейтрофилы, атеросклероз брюшной аорты, сахарный диабет, von Willebrand factor, neutrophils, atherosclerosis of the abdominal aorta, diabetes mellitus