THE LEVEL OF SPONTANEOUS AND ANTI-СD3-STIMULATED СD38 EXPRESSION ON T-LYMPHOCYTES IN CHILDREN WITH AUTOIMMUNE PATHOLOGY
- Authors: Pashnina I.A.1,2
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Affiliations:
- Regional Children's Clinical Hospital № 1
- Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
- Issue: Vol 20, No 2 (2017)
- Pages: 191-194
- Section: Articles
- URL: https://journal-vniispk.ru/1028-7221/article/view/119649
- ID: 119649
Cite item
Abstract
Children of 6-17 years old with systemic lupus erithematosus (n=10), with systemic sclerosis (n=10), with juvenile idiopathic arthritis (n=47) and conditionally healthy controls of corresponding age (n=30) were examined. It was revealed by flow cytometry that after 24-hours incubation (37 °C, 5 % СО2) the spontaneous and anti-СD3-stimulated amount of СD38-positive T-lymphocytes, T-helpers and cytotoxic T-cells in children with rheumatic diseases was decreased in comparison with healthy control.
About the authors
I. A. Pashnina
Regional Children's Clinical Hospital № 1; Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
Author for correspondence.
Russian Federation
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