FUNCTIONAL ACTIVITY OF MONOCYTES IN PREMATURE INFANTS IN NEONATAL DYNAMICS
- Authors: Remizova I.I.1, Shamova K.P.1, Chistyakova G.N.1
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Affiliations:
- FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
- Issue: Vol 20, No 3 (2017)
- Pages: 480-482
- Section: Articles
- URL: https://journal-vniispk.ru/1028-7221/article/view/119782
- ID: 119782
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Abstract
To assess the functional activity of monocytes in preterm infants of different gestational age (22-27.6 weeks and 28-31 weeks) in the dynamics of the neonatal period, cord and peripheral blood were examined. All children with an ENMT at birth had a decreased willingness of effector cells to participate in intercellular interactions (decrease in the number of CD14+ CB 282+ and CD14+ CD157+ monocytes), in infants of gestational age 22-27 weeks - to antigen presentation of the pathogen (decrease in HLA receptor expression -DR+). At the end of the neonatal period, the functional activity of monocytes is restored, the number of CD14+ HLA-DR+ cells exceeds those of full-term children.
About the authors
I. I. Remizova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
K. P. Shamova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
Email: noemail@neicon.ru
Russian Federation
G. N. Chistyakova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
Email: noemail@neicon.ru
Russian Federation
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