INTERRELATION OF PROCALCITONIN AND CD64⁺ WITH BACTEREMIA AND SEVERITY OF ORGAN DYSFUNCTION
- Authors: Kalashnikova A.A.1, Voroshilova T.M.1, Slashcheva O.M.1
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Affiliations:
- A. Nikiforov Russian Centre of Emergency and Radiation Medicine
- Issue: Vol 22, No 2-1 (2019)
- Pages: 293-295
- Section: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/1028-7221/article/view/119796
- DOI: https://doi.org/10.31857/S102872210006605-0
- ID: 119796
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Abstract
To assess the risk of developing infectious complications and sepsis in critically ill patients, a number of laboratory markers are used, the main of which is procalcitonin, the less well known is the expression of CD64 on neutrophils. There is a close correlation between these indicators, however, in some cases, the results of tests for procalcitonin and CD64 contradict each other. The paper assesses the interrelation of procalcitonin and CD64 with bacteremia and severity of organ dysfunction. It was determined that the level of expression of CD64 is closely related to the presence of bacteria in the blood, whereas procalcitonin is not specifi c for bacteremia. A direct correlation was found between the severity of organ dysfunction and both indicators. This interrelation is more signifi cant for procalcitonin. The use of tests for procalcitonin and CD64 in the complex will improve the quality of examination of seriously ill patients.
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About the authors
A. A. Kalashnikova
A. Nikiforov Russian Centre of Emergency and Radiation Medicine
Author for correspondence.
Email: petkova_nas@mail.ru
PhD (Biology), Senior Research Associate, Laboratory of Clinical Immunology,
St. Petersburg
Russian FederationT. M. Voroshilova
A. Nikiforov Russian Centre of Emergency and Radiation Medicine
Email: fake@neicon.ru
PhD (Medicine), Head, Laboratory of Bacteriological Studies,
St. Petersburg
Russian FederationO. M. Slashcheva
A. Nikiforov Russian Centre of Emergency and Radiation Medicine
Email: fake@neicon.ru
Physician, Laboratory of Clinical Immunology,
St. Petersburg
Russian FederationReferences
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