Epidemiology of breast cancer in the Krasnoyarsk region
- 作者: Zyuzyukina A.V.1,2, Komissarovа V.А.2, Gasimli D.D.2, Safontsev I.P.1,2, Zukov R.A.1,2
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隶属关系:
- Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
- Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
- 期: 卷 26, 编号 5 (2021)
- 页面: 163-175
- 栏目: Original Study Articles
- URL: https://journal-vniispk.ru/1028-9984/article/view/111757
- DOI: https://doi.org/10.17816/onco111757
- ID: 111757
如何引用文章
详细
AIMS: To assess the epidemiological indicators and the state of oncological care for patients with breast cancer in the Krasnoyarsk Territory from 2011 to 2021.
MATERIALS AND METHODS: The study presents an analysis of data in the Krasnoyarsk Territory from 2011 to 2021.
Data processing was carried out using Microsoft Excel and Statistica 6.0 software products. The correlation between morbidity and mortality was assessed using Spearman’s correlation analysis, and the result was considered statistically significant at a significance level of p <0.05.
RESULTS: An analysis of the incidence of breast cancer in the Krasnoyarsk Territory from 2011 to 2021 showed an increase in the number of cases by 35.2%. The peak incidence falls on the age range of 55–69 years. The mortality rate for the study period tends to decrease; 1-year mortality decreased from 9.3% to 5.1%. The level of early diagnosis increased to 76.4%, while the rate of advanced forms of breast cancer decreased from 33.5% to 23.6%. There is an increase in the number of patients with breast cancer, registered in the dispensary for 5 years or more, from 54.7% to 62.7%, due to the use of modern clinical recommendations, the use of long courses of adjuvant endocrine therapy (up to 10 years), a wide range and frequency of use of antitumor, including targeted drugs.
Correlation analysis between morbidity and mortality rates for the Krasnoyarsk Territory revealed an average, moderate relationship – the correlation coefficient (r=−0.59; p <0.05). A direct average correlation was obtained between the proportion of newly diagnosed cases of breast cancer at stages III and IV and the 1-year mortality rate (r=0.64; p <0.05). A very strong relationship was found between newly diagnosed cases of breast cancer and diseases detected at early stages (r=0.97; p <0.05).
CONCLUSION: The results obtained indicate the effectiveness of ongoing measures for the prevention and early detection of diseases.
作者简介
Alena Zyuzyukina
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
编辑信件的主要联系方式.
Email: alena-vz@mail.ru
ORCID iD: 0000-0002-6758-4800
SPIN 代码: 6663-3600
Cand. Sci. (Med.), Associate Professor
俄罗斯联邦, Krasnoyarsk; KrasnoyarskValeria Komissarovа
Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
Email: lera21734tkd@gmail.com
ORCID iD: 0000-0002-5862-1761
SPIN 代码: 5808-7020
Statistician
俄罗斯联邦, KrasnoyarskDunya Gasimli
Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
Email: dgasymly@gmail.com
ORCID iD: 0000-0002-0247-9831
SPIN 代码: 2860-9530
Oncologist
俄罗斯联邦, KrasnoyarskIvan Safontsev
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
Email: safoncev@gmail.com
ORCID iD: 0000-0002-8177-6788
SPIN 代码: 1548-5565
Cand. Sci. (Med.), Assistant Lecturer
俄罗斯联邦, Krasnoyarsk; KrasnoyarskRuslan Zukov
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Cancer Center named after A.I. Kryzhanovsky
Email: zukov_rus@mail.ru
ORCID iD: 0000-0002-7210-3020
SPIN 代码: 3632-8415
Dr. Sci. (Med.), Рrofessor
俄罗斯联邦, Krasnoyarsk; Krasnoyarsk参考
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