Protolytic properties of DL-alanyl-DL-methionine and its complexation in aqueous solutions and micellar solutions

Abstract

Dissociation constants of DL-alanyl-DL-methionine have been determined in water and micellar solutions of surfactants (anionic sodium n-dodecyl sulfate, cationic cetylpyridinium chloride, and nonionic Brij 35). It has been established that CuA⁺ and CuH_–1A complexes are formed in water and micellar solutions of sodium n-dodecyl sulfate, while CuA⁺, CuH_–1A, and Cu_–2A^– complexes are formed in micellar solutions of cetylpyridinium chloride and Brij 35. Stability of the complexes depends on micelle surface charge and degrees of binding of individual chemical forms by a micellar pseudophase.