Solubilization of Magnesium Octa[(4′-Benzo-15-Crown-5)Oxy]Phthalocyaninate in Aqueous Micellar Solutions of Hexadecyltriphenylphosphonium Bromide

Abstract

Electronic absorption spectroscopy and fluorimetry have been employed to study the behavior of magnesium octa[(4′-benzo-15-crown-5)oxy]phthalocyaninate (Mg[(B15C5O)₈Pc]) in aqueous micellar solutions of sodium dodecyl sulfate and hexadecyltriphenylphosphonium bromide. Conditions have been found for the existence of monomeric Mg[(B15C5O)₈Pc] complex in surfactant solutions to provide the possibility of using mixed solutions of the complex and cationic surfactants (alkyltriphenylphosphonium bromides) for photodynamic therapy. In surfactant solutions with different concentrations of micelles (c_m) and the complex (c_p), the maximum amount of monomeric Mg[(B15C5O)₈Pc] is achieved at c_m/c_p ≥ 4.