Solubilization as a Method for Creating Hybrid Micellar Templates for the Synthesis of Multifunctional Mesoporous Containers


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Abstract

The solubilization of a water-insoluble biologically active compound, curcumin, in micelles of amphiphilic antimicrobial agents, such as miramistin, ethonium, and cetalkonium, is investigated, and the thermodynamic characteristics of this process are determined. It has been shown that the sol–gel synthesis of multifunctional mesoporous silica containers can be realized using these surfactants’ micelles, which contain solubilized curcumin, as “hybrid” templates.

About the authors

K. A. Naumova

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences; Department of Chemistry, Moscow State University

Email: dema_ol@mail.ru
Russian Federation, Moscow, 119071; Moscow, 119992

O. V. Dement’eva

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Author for correspondence.
Email: dema_ol@mail.ru
Russian Federation, Moscow, 119071

A. V. Zaitseva

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: dema_ol@mail.ru
Russian Federation, Moscow, 119071

V. M. Rudoy

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: dema_ol@mail.ru
Russian Federation, Moscow, 119071

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