Mathematical modeling the formation of a histone octamer

Abstract

A physical model of the interaction of protein molecules and their ability to form complex biological systems for the in vitro case in a solution of monovalent salt has been developed. Their reactive abilities using the methods of electrostatics based on the example of the step-by-step formation of the histone octamer from the H2A, H2B, H3, and H4 proteins have been studied. To analyze the ability of protein molecules to form compounds the matrix of potential energy of interactions between protein molecules in solutions with different concentrations of monovalent salt has been examined.