Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air
- 作者: Kogan V.1, Antonov A.S.1, Chichagov Y.V.1, Victorova-Leclerc O.S.1, Victorov I.V.1, Kozlenok A.V.2
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隶属关系:
- Ioffe Institute
- Almazov Federal Medical Research Center
- 期: 卷 63, 编号 10 (2018)
- 页面: 1543-1551
- 栏目: Experimental Instruments and Technique
- URL: https://journal-vniispk.ru/1063-7842/article/view/202221
- DOI: https://doi.org/10.1134/S1063784218100146
- ID: 202221
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详细
A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.
作者简介
V. Kogan
Ioffe Institute
编辑信件的主要联系方式.
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021
A. Antonov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021
Yu. Chichagov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021
O. Victorova-Leclerc
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021
I. Victorov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021
A. Kozlenok
Almazov Federal Medical Research Center
Email: Viktor.Kogan@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 197341
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