Email this article Optimization of signal-to-noise ratio in the in vivo31P magnetic resonance spectra of the human brain
- Authors: Manzhurtsev A.V.1,2, Semenova N.A.1,2,3, Akhadov T.A.2, Bozhko O.V.2, Varfolomeev S.D.1
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Affiliations:
- Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Research Institute of Children Emergency Surgery and Trauma
- N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
- Issue: Vol 67, No 4 (2018)
- Pages: 647-654
- Section: Full Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/242426
- DOI: https://doi.org/10.1007/s11172-018-2118-3
- ID: 242426
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Abstract
The main problem in 31P magnetic resonance spectroscopy is a low signal-to-noise ratio (SNR) of spectra acquired with clinical magnetic resonance imaging (MRI) scanners. Using spin-spin phosphorus-proton (31P-1H) decoupling and heteronuclear Overhauser effect and taking into account the effect of the longitudinal relaxation time T1 on the SNR, the method for localization and excitation of the region of interest (Image Selected in vivo Spectroscopy pulse sequence) was optimized to increase the SNR in the 31P magnetic resonance spectra of the human brain to ~50% without increasing signal acquisition time.
About the authors
A. V. Manzhurtsev
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Research Institute of Children Emergency Surgery and Trauma
Author for correspondence.
Email: andrey.man.93@gmail.com
Russian Federation, 4 ul. Kosygina, Moscow, Russian Federation, 119334; 22 ul. Bolshaya Polyanka, Moscow, Russian Federation, 119180
N. A. Semenova
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Research Institute of Children Emergency Surgery and Trauma; N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: andrey.man.93@gmail.com
Russian Federation, 4 ul. Kosygina, Moscow, Russian Federation, 119334; 22 ul. Bolshaya Polyanka, Moscow, Russian Federation, 119180; 4 ul. Kosygina, Moscow, Russian Federation, 119334
T. A. Akhadov
Research Institute of Children Emergency Surgery and Trauma
Email: andrey.man.93@gmail.com
Russian Federation, 22 ul. Bolshaya Polyanka, Moscow, Russian Federation, 119180
O. V. Bozhko
Research Institute of Children Emergency Surgery and Trauma
Email: andrey.man.93@gmail.com
Russian Federation, 22 ul. Bolshaya Polyanka, Moscow, Russian Federation, 119180
S. D. Varfolomeev
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: andrey.man.93@gmail.com
Russian Federation, 4 ul. Kosygina, Moscow, Russian Federation, 119334
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