Отправить статью по E-mail Antistress properties of sodium 1-N-acetylamino-1-carboxy-2-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
- Авторы: Zhigacheva I.V.1, Rasulov M.M.2
-
Учреждения:
- M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- State Research Institute for Chemistry and Technology of Organoelement Compounds
- Выпуск: Том 67, № 4 (2018)
- Страницы: 721-725
- Раздел: Full Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/242447
- DOI: https://doi.org/10.1007/s11172-018-2128-1
- ID: 242447
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
The effect of a spatially-hindered phenol, namely sodium 1-N-acetylamino-1-carboxy-2-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, on the functionality of mitochondria of rat liver was studied. Stress impact caused a 3 to 4-fold increase in the fluorescence intensity of the products of lipid peroxidation (LPO) in the membranes of these organelles. The preparation reduced the intensity of LPO to the control level, which was conductive to maintaining high functional activity of the mitochondria. Prevention of mitochondrial dysfunction was probably associated with an increase in the resistance of animals to stress factors.
Об авторах
I. Zhigacheva
M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: zhigacheva@mail.ru
Россия, 4 ul. Kosygina, Moscow, Russian Federation, 119334
M. Rasulov
State Research Institute for Chemistry and Technology of Organoelement Compounds
Email: zhigacheva@mail.ru
Россия, 38 sh. Entuziastov, Moscow, Russian Federation, 105118
Дополнительные файлы
