Pro- and antioxidant properties of uracil derivatives


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Abstract

The review summarizes data on pro- and antioxidant properties of uracil derivatives comprising an important group of pharmacologically active compounds. The presence of OH or NH2 groups at position 5 of the uracil ring was shown to be essential for these compounds to have both antioxidant and prooxidant properties. The mechanism of pro- and antioxidant action is discussed.

About the authors

Yu. I. Murinov

Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences

Author for correspondence.
Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054

S. A. Grabovskii

Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences

Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054

N. N. Kabal’nova

Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences

Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054

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