Pro- and antioxidant properties of uracil derivatives
- Authors: Murinov Y.I.1, Grabovskii S.A.1, Kabal’nova N.N.1
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Affiliations:
- Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences
- Issue: Vol 68, No 5 (2019)
- Pages: 946-954
- Section: Review
- URL: https://journal-vniispk.ru/1066-5285/article/view/243366
- DOI: https://doi.org/10.1007/s11172-019-2505-4
- ID: 243366
Cite item
Abstract
The review summarizes data on pro- and antioxidant properties of uracil derivatives comprising an important group of pharmacologically active compounds. The presence of OH or NH2 groups at position 5 of the uracil ring was shown to be essential for these compounds to have both antioxidant and prooxidant properties. The mechanism of pro- and antioxidant action is discussed.
About the authors
Yu. I. Murinov
Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences
Author for correspondence.
Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054
S. A. Grabovskii
Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences
Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054
N. N. Kabal’nova
Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences
Email: murinov@anrb.ru
Russian Federation, 71 prosp. Oktyabrya, Ufa, 450054
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