Synthesis of ethynyl-3-hydroxyquinoline-4-carboxylic acids
- Authors: Maklakova S.Y.1,2, Chuprov A.D.1, Mazhuga M.P.1, Beloglazkina E.K.1, Zyk N.V.1, Majouga A.G.1,3,2
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Affiliations:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- Laboratory of biomedical nanomaterials, National University of Science and Technology MISiS
- D. I. Mendeleev University of Chemical Technology of Russia
- Issue: Vol 68, No 7 (2019)
- Pages: 1460-1461
- Section: Brief Communications
- URL: https://journal-vniispk.ru/1066-5285/article/view/243440
- DOI: https://doi.org/10.1007/s11172-019-2579-z
- ID: 243440
Cite item
Abstract
3-Hydroxyquinoline-4-carboxylic acids containing ethynyl moiety in the 6th and 8th positions were obtained for the fi rst time. A synthetic approach to aforementioned compounds based on the Sonogashira cross-coupling and the Pfi tzinger reaction was developed. Physicochemical properties of the newly synthesized structures were investigated.
About the authors
S. Yu. Maklakova
Department of Chemistry, M. V. Lomonosov Moscow State University; Laboratory of biomedical nanomaterials, National University of Science and Technology MISiS
Author for correspondence.
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991; 4 Leninskiy prosp., Moscow, 119049
A. D. Chuprov
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991
M. P. Mazhuga
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991
E. K. Beloglazkina
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991
N. V. Zyk
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991
A. G. Majouga
Department of Chemistry, M. V. Lomonosov Moscow State University; D. I. Mendeleev University of Chemical Technology of Russia; Laboratory of biomedical nanomaterials, National University of Science and Technology MISiS
Email: MaklakovaSU@yandex.ru
Russian Federation, Build. 3, 1 Leninskie Gory, Moscow, 119991; 9 Miusskaya pl., Moscow, 125047; 4 Leninskiy prosp., Moscow, 119049
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