


Vol 66, No 6 (2017)
- Year: 2017
- Articles: 32
- URL: https://journal-vniispk.ru/1066-5285/issue/view/14900
Reviews



Full Articles
Quantum chemical studies of azoles
Abstract
The results of theoretical search for model transition states of the electrophilic substitution reaction in 2H-tetrazole (1) without the preliminary formation of N-protonated azolium salts are presented for two routes that were previously suggested by the authors and thermodynamically investigated: A, the attack of molecule 1 by the nucleophile (HO–(aq)) to form the anion to which the electrophile H3O+(aq)) is added and B, the attack of molecule 1 by the same electrophile followed by the addition of the same nucleophile to the specifically solvated protonated species formed in the preceding reaction step. The calculations were performed using the DFT/B3LYP/6-31G(d) method and the scanning procedure of the potential energy surface (PES). Both steps of route A turned out to be nearly barrierless, while in route B only its first step is barrierless and the second one is conjugated with passing an activation barrier of ∼45 kcal mol–1 between non-interacting or weakly interacting reactants and electrophilic substitution products. Unlike the specifically solvated protonated species of 1H-tetrazole in an aqueous solution, a similar species of 2H-tetrazole does not form a prereaction complex with the attacking nucleophile (HO–(aq)) and the five-membered ring is destroyed in fact in the nitrogen-containing reaction product formed after passing the activation barrier. The optimized structure of the transition state differs strongly from the nitrogen-containing structure of the reaction product with the destroyed ring, which was found by scanning of the PES.



Synthesis and structure of ruthenium complexes [Ph3PCH2C6H4F-4]2[RuCl6] and [Ph3PCH2C6H4F-4][trans-RuCl4(dmso-S)2]
Abstract
The reaction of (4-fluorobenzyl)triphenylphosphonium chloride with ruthenium(iii) chloride hydrate in the presence of hydrochloric acid in dimethyl sulfoxide affords the complex [Ph3PCH2C6H4F-4]2[RuCl6]. In the absence of hydrochloric acid, the reaction gives the complex [Ph3PCH2C6H4F-4][trans-RuCl4(dmso-S)2]. The structures of the complexes were studied by 1H, 19F, and 31P NMR spectroscopy and X-ray diffraction.



Reactivity of alkyl iodides in molecular decomposition reactions
Abstract
The experimental results for the concerted molecular decomposition of alkyl iodides RI to olefin and HI were analyzed in terms of the intersecting parabolas model (IPM). The activation energies (E) and rate constants (k) of the earlier unstudied reactions of the concerted molecular decomposition of RI were calculated on the basis of the enthalpy of the reaction and IPM algorithms. The factors that influence on E of RI decay were established: the enthalpy of the reaction, the energy of stabilization of radical R*, the length and force constant of the C—I bond, and the size of the halogen atom. The values of E and k for the backward reactions of HI addition to olefins were estimated.



Adsorption of organic molecules on the highly ordered MCM-41 sorbent modified by different amounts of melamine
Abstract
Thermodynamic characteristics of adsorption of organic molecules on the ordered organosilylated composite MCM-41 with grafted trimethylsilyl groups (MMet) and modified by melamine deposited on the surface were studied by inverse gas chromatography. Mole changes in the internal energy and entropy of adsorption, the dispersion and specific components of the value proportional to the Helmholtz absorption energy, and the contribution of the methyl group to the heat of adsorption were calculated from the specific retention volumes. The change in the retention volumes was established to be determined by the dispersion component of the Helmholtz energy of adsorption, whereas the energy of specific interactions remains almost unchanged. After the adsorbent surface was coated by the second and third melamine layers, the changes in −ΔU and −ΔS for adsorption of the members of the homologous series of n-alkanes are so small that lie within admissible measurement inaccuracies. This phenomenon can be explained by the regularities of alkane adsorption in slit-like pores of the supramolecular structure of melamine.



Colloidal dispersions of molybdenum disulfide with a narrow particle size distribution
Abstract
Colloidal dispersions of MoS2 in DMF were obtained, and a procedure for the preparation of the fraction of particles with the size distribution 1.5 times narrower than that in the original dispersion was developed. It was shown that for the gradual centrifugation of dispersions with an increase in the acceleration from 126g to 2016g the average thickness of nanosheets decreased from 35 to 8 nm and the average lateral sizes decreased from 250 nm to a constant value of 160 nm. A linear dependence of the absorbance of the dispersions on the concentration of MoS2 was established.



Mesoporous SiO2 produced by mineralization of yeast cells as an efficient electrocatalyst for oxygen reduction reaction
Abstract
Mes oporous SiO2 (yeast-SiO2/C) was successfully prepared by mineralization of yeast cell template under different pH values. Analysis of the nitrogen adsorption-desorption isotherms indicated that the pore size distribution of the mesoporous yeast-SiO2 samples significantly varies depending on the pH value used f or biomineralization. Average pore diameters for the samples synthesized at pH 5.0, 7.0, and 11.0 were found to be 7.9, 17.8, and 9.4 nm, respectively. The mineralization ability of silicon ions can be enhanced using conditions with a higher acidity. The air electrodes fabricated using the yeast-SiO2 mesoporous composites exhibited remarkable electrocatalytic activity in oxygen reduction reaction under alkaline conditions. The mesoporous sample synthesized at pH 5.0 showed the highest electrocatalytic performance in the oxygen reduction reaction; this sample has the largest surface area and the highest total pore volume. It is supposed that the mesoporous structure of the nanocomposites predetermined by the yeast cell template significantly reduced the electrochemical polarization and improved mass transport in the air diffusion electrode.



Conversion of ferrous compounds in a flameless combustion wave of hexogen-based systems filled with iron formate and other additives
Abstract
The thermal decomposition of the energetic component and chemical reactions occurring at elevated temperatures in a flameless combustion wave of systems based on hexogen (filled with iron(II) formate and polyisocyanurate binding agent) afford a mixture of iron oxides and iron nitride as nanosized particles. The purposeful change in the ratio of the indicated basis components can provide individual Fe2O3, Fe3O4, or FeO in the conversion products. Additives of anthracene and hydroquinone to the initial composition can result in the formation of predominantly iron carbide in the products, whereas mainly iron nitrides are formed upon the addition of guanidine nitrate or 5-aminotetrazole. The addition of aluminum hydride components to the initial mixture results in the reduction of iron to the zero-valence state in the form of iron—aluminum intermetallic compounds.



Electroluminescence and photovoltaic properties of bis{N-[2-(benzothiazol-2-yl)phenyl]-N-(4-methylphenylsulfonyl)amido}zinc
Abstract
A dual function (electroluminescence and photosensitivity) of devices based on bis{N-[2-(benzothiazol-2-yl)phenyl]-N-(4-methylphenylsulfonyl)amido}zinc was studied. It was shown that both luminescent and photovoltaic properties are strongly dependent on exсiplex formation.



Tetrathiafulvalene-based organic conductors with Pb-containing anions
Abstract
Hybrid compounds containing organic layers composed of tetrathiafulvalenes (BEDT-TTF, BETS, BEDO-TTF) and inorganic layers consisting of anions based on lead bromide were synthesized. The crystal structure of (BEDT-TTF)6Pb3Br10(PhBr) was determined. The temperature dependences of electrical conductivity for the synthesized compounds were measured and the EPR spectra of these compounds were recorded. In the structure of (BEDT-TTF)6Pb3Br10(PhBr), the organic conducting layers of BEDT-TTF molecules alternate with non-conducting layers composed of infinite chains of bromoplumbate anions [Pb3Br9]3–, solvent molecules, and Br– anions. The newly synthesized BEDT-TTF bromoplumbates have similar linewidths of EPR signals, which indicate that their conducting layers have similar structures. The BEDT-TTF bromoplumbates are semiconductors, while temperature-dependent electrical resistivity measurements show the metallic behavior for BEDO-TTF and BETS bromoplumbates.



Synthesis of N-nitro-N′-(trimethylsilyl)carbodiimide
Abstract
Nitration of N,N′-bis(trimethylsilyl)carbodiimide with N2O5 or (NO2)2SiF6 afforded N-nitro-N´-(trimethylsilyl)carbodiimide, the first representative of N-nitro carbodiimides. Its further nitration led to the release of CO2, which is presumably formed in the course of N,N´-dinitrocarbodiimide decomposition. The reactions of N-nitro-N´-(trimethylsilyl)carbodiimide with nucleophiles take place both at the tri methylsilyl group (for example, with NH3) to give nitrocyanamide salts and at the carbodiimide C atom (for example, with Et2NH) to give the corresponding nitroguan idines.



Study of the possibility of quantitative analysis of N,N,N′,N′-tetra-n-octyldiglycolamide by MALDI mass spectrometry
Abstract
Approaches that allow one to carry out quantitative analysis of real objects, solutions of nitric acid after contact with sorbents based on N,N,N′,N′-tetra-n-octyldiglycolamide (TODGA), by MALDI mass spectrometry are considered. The internal standard for the quantitative determination of the target component in real samples containing a high excess of inorganic salts is selected. It is found out that reproducible results can be obtained by the external standard method for a large sampling of experimental data, but the internal standard method can significantly improve the accuracy of quantitative analysis. The use of the internal standard makes it possible to eliminate an inaccuracy related to nonuniformity of sample preparation.



Arenesulfonylation of N-alkylanilines: reaction kinetics and mechanism
Abstract
Kinetic regularities of arenesulfonylation of N-alkylanilines in binary water-organic solvents of variable composition have been studied. The rate constants for these reactions increase with increasing the water content in a system. The steric factor has the decisive influence on reactivity of N-alkylamines. The character of the influence of the composition and nature of a solvent on the rate constants for arenesulfonylation was discussed with the assistance of results of quantum chemical simulation of molecular complexes of the nucleophiles studied with the components of the binary systems. Calculation of potential energy surface for the reaction of N-methylaniline with benzenesulfonyl chloride showed that in the gas phase the process occurs by the SN2 mechanism.



Isomerization of 4-arylamino-1,2-naphthoquinones to 2-arylamino-1,4-naphthoquinones
Abstract
4-Arylamino-1,2-naphthoquinones isomerize into 2-arylamino-1,4-naphthoquinones upon refluxing in acetic acid. The isomerization follows two routes via intermediate 2-hydroxy-1,4-naphthoquinone and 2-arylamino-1,4-naphthoquinone 4-N-arylimines.



A comparative study of the reactions of fluorinated oxi- and thiiranes with acyl chlorides
Abstract
The CoCl2-catalyzed reactions of fluorinated 1,2-oxi- and thiiranes with acyl chlorides were studied. It was found that a regioselective heterocycle opening reaction resulted in two isomers having normal and abnormal structure in a ratio predetermined by the substituents in both the starting heterocycles and acyl chlorides.



Synthesis of substituted 3-acyl-1-hydroxyindoles and azoles on their basis
Abstract
A general approach to the synthesis of new 3-acetyl-substituted pyrrolo[3,4-f]indole-5,7-diones, 3-[3-(dimethylamino)acryloyl]-1-methoxypyrrolo[3,4-f]indole-5,7-diones and similar indole-5,6-dicarbonitriles has been developed. Dimethylaminoacryloyl derivatives synthesized on their basis regioselectively reacted with hydrazine hydrochlorides and hydroxylamine with the formation of the corresponding 5-substituted azoles.



5-Hydroxy-2,3-dihydrobenzofuran-derived polyfunctional antioxidants
Abstract
2-Dodecylthiomethyl-5-hydroxy-2,3-dihydrobenzofurans, new sulfur-containing analogs of tocopherols, were synthesized based on methylphenols through the intermediate preparation of 4-alkoxy-2-allylphenols and then 5-alkoxy-2-iodomethyl-2,3-dihydrobenzofurans.



Synthesis of substituted disulfonyl-containing polycyclic azines with the bridgehead nitrogen atom. Effects of the structure of 3-substituted pyridinium ylides on the regioselectivity of their reactions with E-1,2-di(alkylsulfonyl)-1,2-dichloroethenes
Abstract
Heating the substituted pyridinium and isoquinolinium salts with E-1,2-di(alkylsulfonyl)-1,2-dichloroethenes in either chloroform or acetone in the presence of three-fold excess of Et3N gave high yields of substituted 1,2-di(alkylsulfonyl)indolizines and 1,2-di(alkylsulfonyl) pyrrolo[2,1-a]isoquinolines, respectively. Effects of the structure of 3-substituted pyridinium ylides on the regioselectivity of their reaction with E-1,2-di(alkylsulfonyl)-1,2-dichloroethenes were revealed. It was shown that the presence of electron-releasing and electron-withdrawing substituents in the pyridinium ylide favors the formation of 8-substituted and 6-substituted 1,2-(dialkylsulfonyl)indolizines, respectively.



Synthesis and properties of 1,2-dihydro-4(3H)-quinazolinones
Abstract
We modified the preparative-scale method for the synthesis of 2-aryl 1,2-dihydro-4(3H)-quinazolinone derivatives obtained in high yields by the reaction of new and commercially available aromatic aldehydes with anthranilic acid amides. A series of quinazolinone derivatives possessing anticancer and antiparasitic activities, as well as capable of preventing the progress of neurodegenerative diseases were characterized. There are grounds for clinical trials of these substances in order to select compounds being promising for clinical application.



Asymmetric Ir-catalyzed hydrogenation of 1,5-benzodiazepinones using mixtures of ligands
Abstract
The catalytic hydrogenation of benzodiazepinones using metal complexes with phosphite and phosphoramidite ligands was carried out for the first time. The mixed-ligand catalytic systems containing a chiral phosphoramidite or phosphite in combination with an achiral phosphine were shown to exhibit a higher enantioselectivity compared to catalysts containing homocombinations of chiral ligands.






Optimization of the key steps of synthesis and study of the fundamental physicochemical properties of high energy compounds — 4-(2,2,2-trinitroethyl)-2,6,8,10,12-pentanitrohexaazaisowurtzitane and 4,10-bis(2,2,2-trinitroethyl)-2,6,8,12-tetranitrohexaazaisowurtzitane
Abstract
The key steps of the synthesis of two high energy compounds, namely, 4-(2,2,2-trinitroethyl)-2,6,8,10,12-pentanitrohexaazaisowurtzitane and 4,10-bis(2,2,2-trinitroethyl)-2,6,8,12-tetranitrohexaazaisowurtzitane, were optimized. Their enthalpy of formation, density, impact and friction sensitivity, and thermal stability were experimentally determined.



1-Chloro-1,3-dimethyl-1,3-diorganyl-3-(trimethylsilylamino)disiloxanes
Abstract
The main products of the reaction of 1,3-dichloro-1,3-dimethyl-1,3-diorganyldisiloxanes with hexamethyldisilazane (molar ratio 1 : 1, 20 °C) are the earlier unknown linear 1-chloro-1,3-dimethyl-1,3-diorganyl-3-(trimethylsilylamino)disiloxanes of the general formula ClMeRSiOSiMeRNHSiMe3 (1) (R = ClCH2 (a), Me (b), Vin (c), Ph (d)) obtained in up to 53—72% yield and 1,3-dimethyl-1,3-diorganyl-1,3-bis(trimethylsilylamino)disiloxanes of the general formula (Me3SiNH)MeRSiOSiMeR(NHSiMe3) (2a—d) (7—12% yield). Thermolysis of compounds 1a—d leads to the formation of cyclic silazaoxanes. A plausible scheme for their formation was suggested.



Manganese complexes with different ligand environments in the polymerization of methyl methacrylate and styrene
Abstract
Polymerization of methyl methacrylate and styrene in the presence of manganese cyclopentadienylcarbonyl complexes containing π-alkene (methyl methacrylate), vinylidene, and allenylidene ligands was investigated. It was found that metal complex ligand environment plays a key role in the initiation of the polymerization and in the regulation of the molecular weight characteristics of synthesized polymers. In particular, the manganese complexes with cumulenylidene ligands are capable to initiate spontaneously polymerization of vinyl monomers. The process of polymerization proceeds to high conversions (over 90%), and the resulting polymers are characterized by high values of molecular weight and relatively broad molecular weight distribution.



Kinetic parameters of cationic polymerization of 1,3-dienes
Abstract
A new technique for the determination of the concentration of active centers of polymerization and propagation rate constants for processes of cationic polymerization of conjugated dienes was proposed. The method consists of the quantitative calculation from the 13C NMR spectra of the concentration of the initial units of the polymer chain polydienes synthesized at different monomer conversions and the subsequent extrapolation of the obtained values to the zero monomer conversion. Using the proposed procedure, the chain propagation rate constants were determined for the cationic polymerization of isoprene and 1,3-pentadiene in the presence of a titanium tetrachloride–tert-butyl chloride catalytic system.



New star-like polydimethylsiloxanes: synthesis, properties, and application
Abstract
New star-like polydimethylsiloxanes with a cis-tetraphenylcyclotetrasilsesquioxane fragment as the core (branching center) were synthesized and characterized. The thermophysical properties of the obtained polymers were studied by DSC and TGA. The epoxy resin surface modified with the obtained polymers was analyzed by XPS.



Nanocomposites with silver nanoparticles based on copolymer of 1-vinyl-1,2,4-triazole with N-vinylpyrrolidone
Abstract
New functional silver polymer nanocomposites were synthesized using copolymer of 1-vinyl-1,2,4-triazole with N-vinylpyrrolidone as a stabilizer of the formed metal nanoparticles. The formation of a metal phase in the nanosized state was confirmed by powder X-ray diffraction. According to transmission electron microscopy, the obtained polymer nanocomposites consist of isolated nanoparticles with diameter from 1 to 12 nm having a predominately spheric form, which are uniformly distributed throughout the bulk of the polymeric matrix. The nanocomposites are characterized by different degrees of nanoparticle size distribution, which is determined by the ability of the polymeric matrix to stabilize different metal content.



Sorption concentration of palladium by a nitrogen-containing heterocyclic copolymer
Abstract
A novel cross-linked copolymer of 1-vinyl-1,2,4-triazole and N,N′-methylene-bis-acrylamide was synthesized via free radical copolymerization. Sorption capacity of the copolymer toward palladium chloride(ii) in acid aqueous solutions was investigated. Sorption properties and efficiency of the polymer as a sorbent were evaluated. Mechanism of the copolymer interaction with palladium complex was identified by methods of IR- and Raman spectroscopy and elemental analysis.



Peculiarities of N-vinylpyrrolidone copolymerization with vinyl acetate in the presence of tributylborane and 1,4-benzoquinone
Abstract
Copolymerization of N-vinylpyrrolidone with vinyl acetate in the presence of tributylborane and 1,4-benzoquinone has been investigated. The curves of copolymer composition and relative reactivity of monomers were obtained. An introduction of tributylborane in the monomer mixture leads to the formation of complex with N-vinylpyrrolidone. Molecular weight of the copolymers and the rate of the copolymerization decreases with the addition of tributylborane and 1,4-benzoquinone compare to conventional copolymerization initiated by dicyclohexyl peroxydicarbonate. The curve of the copolymer composition acquires an S-shape. Triad composition of the copolymers differs from the theoretical values. The reason for the observed pheno mena is realization of the effect of preferential solvation (bootstrap-effect).



Synthesis of ethyl α-nitro-β-trifluoromethyl acrylate and β-trifluoromethyl-substituted tryptophan analogs and their plant growth regulating activity
Abstract
Ethyl α-nitro-β-trifluoromethyl acrylate was synthesized by nucleophile-catalyzed reaction of ethyl nitroacetate with excess trifluoroacetaldehyde methyl hemiacetal and subsequent dehydration of the intermediate alcohol with P2O5. The synthesized nitro olefin regioselectively reacts with the substituted indoles to give fluorinated 3-indolyl-2-nitrobutyrates, which were converted into the corresponding β-trifluoromethyl-substituted tryptophan analogs via the nitro group reduction followed by saponification of the ethoxycarbonyl group. In the step of synthesis of amino ester, the 2-methylindole derivative was resolved into diastereomers, which were transformed to the corresponding acids separately. It was found that the synthesized β-trifluoromethyltryptophans have plant-growth regulating activity apparently attributable to their metabolic transformations into substituted α-trifluoromethylindol-3-ylacetic acids.



Synthesis and antimycobacterial activity of N-isonicotinoyl-N′-alkylideneferrocenecarbohydrazides
Abstract
Acylation of ferrocenoylhydrazones with isonicotinoyl chloride hydrochloride in pyridine was used to obtain a number of new N-isonicotinoyl-N′-ylideneferrocenecarbohydrazides in 50–95% yields. The obtained compounds were characterized by NMR and IR spectroscopy and mass-spectrometry. Some of the obtained compounds were found to exhibit pronounced antimycobacterial activity against the Mycobacterium rubrum strain and to have no toxicity with respect to the P. aeruginosa, E. coli, S. aureus, B. subtilis, and C. albicans strains.



Brief Communications
Synthesis of new pyrido[2′,3′:3,4]pyrazolo[5,1-c]-[1,2,4]triazin-4(6H)-one derivatives
Abstract
New pyrido[2′,3′:3,4]pyrazolo[5,1-c][1,2,4]triazin-4(6H)-one derivatives were synthesized from accessible 1,2,4-triazine and pyrazolo[5,1-c][1,2,4]triazine derivatives. Specific features of the reactions were studied and spectral characteristics of the compounds are reported.


