Email this article Synthesis and physicochemical properties of the pectin complexes with Xymedon
- Authors: Minzanova S.T.1, Mironov V.F.1, Khabibullina A.V.1, Arkhipova D.M.1, Mironova L.G.1, Ryzhkina I.S.1, Sergeeva S.Y.1, Murtazina L.I.1, Smolobochkina F.R.1, Milyukov V.A.1
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Affiliations:
- A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
- Issue: Vol 68, No 2 (2019)
- Pages: 405-410
- Section: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/243261
- DOI: https://doi.org/10.1007/s11172-019-2400-z
- ID: 243261
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Abstract
The formation of stable complexes of pectin polysaccharides with 1-(2-hydroxyethyl)-4,6- dimethyl-1,2-dihydropyrimidin-2-one (Xymedon drug) was shown by UV and IR spectro scopy, dynamic light scattering, and polarimetry. The stoichiometry of the complexes was determined, and their synthesis conditions were optimized. Specific features of the thermal decomposition of pectin and synthesized complexes with Xymedon were studied by the TG/DSC method. The results obtained allow one to substantially extend ranges of using Xymedon in medicine.
About the authors
S. T. Minzanova
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Author for correspondence.
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
V. F. Mironov
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
A. V. Khabibullina
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
D. M. Arkhipova
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
L. G. Mironova
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
I. S. Ryzhkina
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
S. Yu. Sergeeva
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
L. I. Murtazina
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
F. R. Smolobochkina
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
V. A. Milyukov
A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: minzanova@iopc.ru
Russian Federation, 8 ul. Akad. Arbusova, Kazan, 420088
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