电邮这篇文章 Inhibition of acid phospholipase A1 activity by the complex of tris(2-hydroxyethyl)amine with zinc bis(2-methylphenoxyacetate)
- 作者: Abzaeva K.A.1, Rasulov M.M.2, Zhigacheva I.V.3
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隶属关系:
- A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences
- State Research Institute of Chemistry and Technology of Organoelement Compounds
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- 期: 卷 68, 编号 5 (2019)
- 页面: 1122-1124
- 栏目: Brief Communications
- URL: https://journal-vniispk.ru/1066-5285/article/view/243390
- DOI: https://doi.org/10.1007/s11172-019-2529-9
- ID: 243390
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详细
Studies in the atherosclerosis model in rabbits showed that the complex of tris(2-hydroxyethyl)amine with zinc bis(2-methylphenoxyacetate) (zincatrane) modulates lipid metabolism in the liver and reduces activity of a lysosomal lipolytic enzyme of the hydrolase class. Zincatrane was proposed for use as an acid phospholipase A1 inhibitor to increase the resistance of the vascular system to cholesterol and prevent atherosclerosis.
作者简介
K. Abzaeva
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: abzaeva@irioch.irk.ru
俄罗斯联邦, 1 ul. Favorskogo, Irkutsk, 664033
M. Rasulov
State Research Institute of Chemistry and Technology of Organoelement Compounds
Email: abzaeva@irioch.irk.ru
俄罗斯联邦, 38 Entuziastov shosse, Moscow, 105118
I. Zhigacheva
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: abzaeva@irioch.irk.ru
俄罗斯联邦, 4 ul. Kosygina, Moscow, 119334
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