电邮这篇文章 Trifluoromethylated 5-aminoderivatives of (indol-3-yl)acetic acid
- 作者: Vorobyeva D.V.1, Vasilyeva T.P.1, Osipov S.N.1
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隶属关系:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- 期: 卷 67, 编号 8 (2018)
- 页面: 1459-1466
- 栏目: Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/242828
- DOI: https://doi.org/10.1007/s11172-018-2240-2
- ID: 242828
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详细
New CF3-containing derivatives of (5-aminoindol-3-yl)acetic acid were synthesized from 5-nitroindole and trifluoropyruvate or 2-diazotrifluoropropionate. Their reactions with isocyanates allowed us to obtain the series of new ureas, including sulfonylureas, containing a pharmacophore moiety of α-(trifluoromethyl)indolylacetic acid.
作者简介
D. Vorobyeva
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: osipov@ineos.ac.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
T. Vasilyeva
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: osipov@ineos.ac.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
S. Osipov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: osipov@ineos.ac.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
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